2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide

Base Information

Chemical Name:2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide
CAS No.:247592-67-2
Molecular Formula:C₁₇H₁₇NO₄
Molecular Weight:299.326
Hs Code.:
DSSTox Substance ID:DTXSID001195517
Mol file:247592-67-2.mol

Synonyms:2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide;247592-67-2;2-(4-Formyl-2-methoxy-phenoxy)-N-o-tolyl-acetamide;2-(4-Formyl-2-methoxyphenoxy)-N-(o-tolyl)acetamide;Oprea1_164491;Oprea1_180490;SCHEMBL15330901;DTXSID001195517;BBL023932;MFCD01326190;STK353572;AKOS000196318;VS-07568;CS-0240349;EN300-227960;(4-formyl-2-methoxyphenoxy)-n-(o-tolyl)acetamide;Z19660672

Suppliers and Price of 2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(4-Formyl-2-methoxy-phenoxy)-N-o-tolyl-acetamide
1g
$ 378.00

Crysdot
2-(4-Formyl-2-methoxyphenoxy)-N-(o-tolyl)acetamide 97%
1g
$ 307.00

American Custom Chemicals Corporation
2-(4-FORMYL-2-METHOXY-PHENOXY)-N-O-TOLYL-ACETAMIDE 95.00%
500MG
$ 768.08

Total 6 raw suppliers

Chemical Property of 2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide

Chemical Property:

Boiling Point:525.5±45.0 °C(Predicted)
PKA:13.25±0.70(Predicted)
Density:1.232±0.06 g/cm3(Predicted)
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:299.11575802
Heavy Atom Count:22
Complexity:374

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-Formyl-2-methoxy-phenoxy)-N-o-tolyl-acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)COC2=C(C=C(C=C2)C=O)OC

Technology Process of 2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide

There total 3 articles about 2-(4-formyl-2-methoxyphenoxy)-N-(2-methylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₀H₉ClO₄

: 95-53-4
o-toluidine

: 247592-67-2
2-(4-formyl-2-methoxyphenoxy)-N-(o-tolyl)acetamide

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 4.5h;
DOI:10.1016/j.bmcl.2021.128194

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 247592-67-2
2-(4-formyl-2-methoxyphenoxy)-N-(o-tolyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water / 1.67 h / Reflux

2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C

3: sodium hydrogencarbonate / dichloromethane / 4.5 h / 20 °C

With thionyl chloride; sodium hydrogencarbonate; N,N-dimethyl-formamide; sodium hydroxide; In dichloromethane; water;
DOI:10.1016/j.bmcl.2021.128194

Reference yield:

: 3-methoxy-4-(2-oxopropoxy)benzaldehyde

: 247592-67-2
2-(4-formyl-2-methoxyphenoxy)-N-(o-tolyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C

2: sodium hydrogencarbonate / dichloromethane / 4.5 h / 20 °C

With thionyl chloride; sodium hydrogencarbonate; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bmcl.2021.128194