2-hydroxyacetophenone nicotinic acid hydrazone

Base Information

• Chemical Name: 2-hydroxyacetophenone nicotinic acid hydrazone
• CAS No.: 74734-33-1
• Molecular Formula: C₁₄H₁₃N₃O₂
• Molecular Weight: 255.276
• Mol file: 74734-33-1.mol

Synonyms:

Chemical Property of 2-hydroxyacetophenone nicotinic acid hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxyacetophenone nicotinic acid hydrazone

There total 1 articles about 2-hydroxyacetophenone nicotinic acid hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

picolinic acid hydrazide (1452-63-7) + o-hydroxyacetophenone (118-93-4,104809-67-8) → 2-hydroxyacetophenone nicotinic acid hydrazone (74734-33-1)

Guidance literature:

With ethanol;

DOI:10.1021/ja01117a519

Reference yield:

o-hydroxyacetophenone 2-picoloyl hydrazone (74734-33-1) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → Co(2+)*2C5H4NCONHNC(CH3)C6H4OH*2Cl(1-)*H2O = [Co(C5H4NCONHNC(CH3)C6H4OH)2]Cl2*H2O

Guidance literature:

In methanol; ethanol; acetone; soln. of the org. compd. in acetone/alcohol (1:1) treated with a soln. of the metal salt in MeOH, refluxed for 1 h; filtered, washed with MeOH, air dried, elem. anal.;

DOI:10.1016/0022-1902(81)80437-X

Reference yield:

o-hydroxyacetophenone 2-picoloyl hydrazone (74734-33-1) + nickel dichloride (83864-14-6) → Ni(2+)*2C5H4NCONHNC(CH3)C6H4OH*2Cl(1-)*H2O = [Ni(C5H4NCONHNC(CH3)C6H4OH)2]Cl2*H2O

Guidance literature:

In methanol; ethanol; acetone; soln. of the org. compd. in acetone/alcohol (1:1) treated with a soln. of the metal salt in MeOH, refluxed for 1 h; filtered, washed with MeOH, air dried, elem. anal.;

DOI:10.1016/0022-1902(81)80437-X

upstream raw materials:

picolinic acid hydrazide

o-hydroxyacetophenone

Refernces

• 1、 Dutta, R. L.,Das, B. R.. "Some Selected Lanthanide Complexes of Schiff Bases Derived by Condensing Salicylaldehyde, o-Hydroxyacetophenone and 2-Hydroxynaphthaldehyde with Benzoyl and 2-Picoloyl Hydrazides". . p. 207 - 210. Retrieved 2007/10/02.