(z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide

Base Information

• Chemical Name: (z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide
• CAS No.: 1433999-78-0
• Molecular Formula: C₈H₉BrN₂O
• Molecular Weight: 229.076
• Mol file: 1433999-78-0.mol

Synonyms:

Chemical Property of (z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide

There total 1 articles about (z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

4-Bromophenylacetonitrile (16532-79-9) → (z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide (1433999-78-0,422560-40-5)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In ethanol; at 20 ℃; for 7h; Reflux;

DOI:10.1021/jm701613h

Reference yield: 80.0%

(z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide (1433999-78-0,422560-40-5) + (E)-3-phenylacrylic acid (140-10-3) → N-((E)-2-(4-bromophenyl)-1-(hydroxyimino)ethyl)cinnamamide

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 50 ℃;

Reference yield: 50.0%

(z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide (1433999-78-0,422560-40-5) + ethyl chlorocarbonylacetate (36239-09-5) → C13H13BrN2O3 (1028344-70-8)

Guidance literature:

(z)-2-(4-bromophenyl)-N′-hydroxyacetimidamide; With sodium hydride; In toluene; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

ethyl chlorocarbonylacetate; In toluene; mineral oil; Inert atmosphere; Reflux;

DOI:10.1021/jm701613h

upstream raw materials:

4-Bromophenylacetonitrile

Downstream raw materials:

C₁₃H₁₁BrN₂O₄

C₁₃H₁₃BrN₂O₃