Diethylphosphinic acid

Base Information

• Chemical Name: Diethylphosphinic acid
• CAS No.: 813-76-3
• Molecular Formula: C4H11O2P
• Molecular Weight: 122.104
• DSSTox Substance ID: DTXSID20400487
• Nikkaji Number: J21.042K
• Wikidata: Q82203490
• Mol file: 813-76-3.mol

Synonyms:diethylphosphinic acid;813-76-3;DIETHYLPHOSPHINICACID;SCHEMBL191734;DTXSID20400487;AKOS006275551;F71351;A922794

Chemical Property of Diethylphosphinic acid

Chemical Property:

• Vapor Pressure: 6.82E-05mmHg at 25°C
• Melting Point: 18.5°C
• Refractive Index: 1.413
• Boiling Point: 320 °C at 760 mmHg
• PKA: 3.18±0.50(Predicted)
• Flash Point: 135.5 °C
• PSA: 47.11000
• Density: 1.05 g/cm³
• LogP: 1.29660
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 122.04966659
• Heavy Atom Count: 7
• Complexity: 81.7

Purity/Quality:

97% ^*data from raw suppliers

DIETHYLPHOSPHINICACID 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCP(=O)(CC)O

Technology Process of Diethylphosphinic acid

There total 21 articles about Diethylphosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

methyl diethylphosphinate (5689-41-8) → diethylphosphinic acid (813-76-3)

Guidance literature:

With 1,1,1,2,2,3,3-heptachloropropane; at 180 ℃; for 14.5h;

DOI:10.1007/s11176-005-0157-6

Reference yield: 70.0%

benzyl(diethyl)phosphine oxide (4519-78-2) + benzaldehyde (100-52-7) → (E)-1,2-diphenyl-ethene (103-30-0) + diethylphosphinic acid (813-76-3)

Guidance literature:

benzyl(diethyl)phosphine oxide; With sodium amide; In tetrahydrofuran; at 58 - 60 ℃; for 1h;

benzaldehyde; In tetrahydrofuran; for 1h; Heating;

DOI:10.1023/A:1026340532022

Reference yield: 45.0%

1,1,1,2,2-pentabromoethane (75-95-6) + methyl diethylphosphinate (5689-41-8) → 1,1,2,2-tetrabromoethene (79-28-7) + diethylphosphinic acid (813-76-3)

Guidance literature:

at 100 ℃; for 13h;

DOI:10.1134/S1070363206070293

upstream raw materials:

tetraethyldiphosphine disulfide

Diethylphosphine

diethylphenylphosphine oxide

diethylzinc

Downstream raw materials:

diethylphosphinic chloride

diethylphosphinic acid anhydride

diethyl-dichloromethylphosphine oxide

diethylthiophosphoryl chloride