cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

Base Information

Chemical Name:cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine
CAS No.:141958-00-1
Molecular Formula:C₂₈H₃₀Cl₂N₂O
Molecular Weight:481.465
Hs Code.:

cis-2-<bis(4-chlorophenyl)methyl>-N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

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Technology Process of cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

There total 3 articles about cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-[Bis-(4-chloro-phenyl)-methyl]-1-aza-bicyclo[2.2.2]oct-(3E)-ylidene]-(2-methoxy-benzyl)-amine

: 141958-00-1
cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

Guidance literature:: With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; for 72h; Yield given; Ambient temperature;
DOI:10.1021/jm00092a009

Reference yield:

: 6850-57-3
2-methoxybenzylamine

: 141958-00-1
cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: camphorsulfonic acid / toluene / 18 h / Heating

2: 9-BBN / tetrahydrofuran / 72 h / Ambient temperature

With 9-borabicyclo[3.3.1]nonane dimer; camphor-10-sulfonic acid; In tetrahydrofuran; toluene;
DOI:10.1021/jm00092a009

Reference yield:

: 141957-91-7
2-(4,4'-Dichlorobenzhydryl)-3-quinuclidinon

: 141958-00-1
cis-2--N-<(2-methoxyphenyl)methyl>-1-azabicyclo<2.2.2>octan-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: camphorsulfonic acid / toluene / 18 h / Heating

2: 9-BBN / tetrahydrofuran / 72 h / Ambient temperature

With 9-borabicyclo[3.3.1]nonane dimer; camphor-10-sulfonic acid; In tetrahydrofuran; toluene;
DOI:10.1021/jm00092a009