N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide

Base Information

• Chemical Name: N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide
• CAS No.: 210109-75-4
• Molecular Formula: C₃₄H₃₆N₆O₆
• Molecular Weight: 624.696

Synonyms:

Chemical Property of N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide

There total 3 articles about N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) → N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide (210109-75-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / pyridine / 1 h / Ambient temperature

2: 1.) Me₃SiCl / 1.) pyridine, r.t., 15 min; 2.) pyridine, r.t., 3 h

With chloro-trimethyl-silane; In pyridine;

DOI:10.1002/hlca.19980810527

Reference yield:

8-Aza-2'-deoxy-adenosine (4229-57-6,4229-58-7,34698-66-3) → N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide (210109-75-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / pyridine / 1 h / Ambient temperature

2: 1.) Me₃SiCl / 1.) pyridine, r.t., 15 min; 2.) pyridine, r.t., 3 h

With chloro-trimethyl-silane; In pyridine;

DOI:10.1002/hlca.19980810527

Reference yield:

2-Methylpropionic anhydride (97-72-3) + (2R,3S,5R)-5-(7-Amino-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol (210109-71-0) → N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide (210109-75-4)

Guidance literature:

With methanol; trimethylsilylazide; Yield given. Multistep reaction; 1) 25 deg C;

DOI:10.1016/S0040-4039(98)00283-4

upstream raw materials:

2-Methylpropionic anhydride

(2R,3S,5R)-5-(7-Amino-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol

4,4'-dimethoxytrityl chloride

8-Aza-2'-deoxy-adenosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 210109-75-4 N-(3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-isobutyramide

Send

Send

Metric Ton KG G Pound L ML

Send

Send