2-methyl-6-phenyl-2-heptene

Base Information

• Chemical Name: 2-methyl-6-phenyl-2-heptene
• CAS No.: 53210-18-7
• Molecular Formula: C₁₄H₂₀
• Molecular Weight: 188.313
• Mol file: 53210-18-7.mol

Synonyms:

Chemical Property of 2-methyl-6-phenyl-2-heptene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-6-phenyl-2-heptene

There total 6 articles about 2-methyl-6-phenyl-2-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-6-phenyl-heptan-3-ol (855957-60-7) → 2-methyl-6-phenyl-2-heptene (53210-18-7)

Guidance literature:

With potassium hydrogensulfate; at 150 - 160 ℃; under 100 Torr;

Reference yield:

(1-iodopropan-2-yl)benzene (1459-01-4) + prenyl tributylstannane (104108-29-4) → 2-methyl-6-phenyl-2-heptene (53210-18-7) + C14H20 (1612882-53-7)

Guidance literature:

prenyl tributylstannane; With n-butyllithium; In tetrahydrofuran; at -78 - -20 ℃; for 0.5h; Inert atmosphere;

(1-iodopropan-2-yl)benzene; In tetrahydrofuran; at -78 ℃; for 0.5h; Reagent/catalyst; Temperature; Overall yield = 100 %Chromat.;

DOI:10.1002/adsc.201300250

Reference yield:

3-phenyl-1-butanol (2722-36-3) → 2-methyl-6-phenyl-2-heptene (53210-18-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 96 percent / PPh₃-Br₂ complex

2.1: Mg

2.2: 56 percent / 0.5 h / 0 °C

With magnesium; triphenylphosphine dibromide 1:1 addition complex; 3.1: Wittig coupling;

DOI:10.1016/j.tet.2006.07.102

upstream raw materials:

2-methyl-6-phenyl-heptan-3-ol

bromobenzene

6-Methyl-hept-5-en-2-on

triphenylphosphonio-1-methylethanide

Refernces

• 1、 Stratakis, Manolis,Raptis, Christos,Sofikiti, Nikoletta,Tsangarakis, Constantinos,Kosmas, Giannis,Zaravinos, Ioannis-Panagiotis,Kalaitzakis, Dimitris,Stavroulakis, Dimitris,Baskakis, Constantinos,Stathoulopoulou, Aggeliki. "Intrazeolite photooxygenation of chiral alkenes. Control of facial selectivity by confinement and cation-π interactions". . p. 10623 - 10632. Retrieved 2007/10/03.