Technology Process of C17H14F2O3
There total 3 articles about C17H14F2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-Bromobenzoic acid;
With
n-butyllithium;
In
tetrahydrofuran;
at -105 - -70 ℃;
Inert atmosphere;
C12H15F2NO2;
In
tetrahydrofuran;
at -105 - -50 ℃;
for 1.25h;
Inert atmosphere;
DOI:10.1002/anie.201105138
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylammonium dihydrofluoride; ethanaminium,N-(difluoro-λ4-sulfanylidene)-N-ethyl-,tetrafluoroborate / dichloromethane / 24 h / 20 °C / Inert atmosphere
2.1: isopropylmagnesium chloride / tetrahydrofuran / 0.5 h / -10 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran / -105 - -70 °C / Inert atmosphere
3.2: 1.25 h / -105 - -50 °C / Inert atmosphere
With
n-butyllithium; isopropylmagnesium chloride; triethylammonium dihydrofluoride; ethanaminium,N-(difluoro-λ4-sulfanylidene)-N-ethyl-,tetrafluoroborate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.201105138
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: isopropylmagnesium chloride / tetrahydrofuran / 0.5 h / -10 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / -105 - -70 °C / Inert atmosphere
2.2: 1.25 h / -105 - -50 °C / Inert atmosphere
With
n-butyllithium; isopropylmagnesium chloride;
In
tetrahydrofuran;
DOI:10.1002/anie.201105138
