Methanesulfonic acid, trifluoro-, 3-acetylphenyl ester

Base Information

• Chemical Name: Methanesulfonic acid, trifluoro-, 3-acetylphenyl ester
• CAS No.: 138313-22-1
• Molecular Formula: C9H7F3O4S
• Molecular Weight: 268.213
• Mol file: 138313-22-1.mol

Synonyms:

Chemical Property of Methanesulfonic acid, trifluoro-, 3-acetylphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid, trifluoro-, 3-acetylphenyl ester

There total 1 articles about Methanesulfonic acid, trifluoro-, 3-acetylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trifluoromethylsulfonic anhydride (358-23-6) + 3-Hydroxyacetophenone (121-71-1) → 3-acetylphenyl trifluoromethanesulfonate (138313-22-1)

Guidance literature:

With 2,6-dimethylpyridine; dmap; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1016/S0040-4039(00)61127-9

Reference yield: 97.0%

3-acetylphenyl trifluoromethanesulfonate (138313-22-1) → 3-Hydroxyacetophenone (121-71-1)

Guidance literature:

With tetraethylammonium hydroxide; In 1,4-dioxane; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2004.06.104

Reference yield: 96.0%

3-acetylphenyl trifluoromethanesulfonate (138313-22-1) + cyclopentene (142-29-0) → 1-(m-acetophenyl)cyclopentene

Guidance literature:

With 1,2-dimethoxybenzene; bis(1,1,1,5,5,5-hexafluoro-2,4-pentanedionato)palladium(II); 1,3-bis-(diphenylphosphino)propane; lithium carbonate; at 120 ℃; for 52h; Inert atmosphere;

DOI:10.1002/chem.201204427

upstream raw materials:

trifluoromethylsulfonic anhydride

3-Hydroxyacetophenone

Downstream raw materials:

methyl 3-acetylbenzoate

2-(3-acetylphenyl)-2-propen-1-ol

1-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-ethanone

3-Hydroxyacetophenone

Refernces

• 1、 Wu, Xiaojin,Lu, Yunpeng,Hirao, Hajime,Zhou, Jianrong. "Achieving vinylic selectivity in Mizoroki-heck reaction of cyclic olefins". supporting information. p. 6014 - 6020. Retrieved 2013/06/26.
• 2、 Goossen, Lukas J.,Linder, Christophe,Rodriguez, Nuria,Lange, Paul P.. "Biaryl and aryl ketone synthesis via Pd-catalyzed decarboxylase coupling of carboxylate salts with aryl triflates". supporting information; experimental part. p. 9336 - 9349. Retrieved 2010/04/03.