Technology Process of C26H29F3O6
There total 6 articles about C26H29F3O6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; dicyclohexyl-carbodiimide;
In
dichloromethane;
at 20 ℃;
for 20h;
Inert atmosphere;
DOI:10.1021/ml200254h
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium osmate; K3Fe(CN)6; (DHQD)2PHAL; methanesulfonamide; potassium carbonate / water; tert-butyl alcohol / 36 h / 0 °C
2.1: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 °C / Inert atmosphere
4.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 2 h / -78 - -45 °C / Inert atmosphere
4.2: 2 h / -78 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
6.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 h / 20 °C / Inert atmosphere
With
1H-imidazole; dmap; potassium osmate; methanesulfonamide; K3Fe(CN)6; (DHQD)2PHAL; tetrabutyl ammonium fluoride; potassium carbonate; dicyclohexyl-carbodiimide; lithium diisopropyl amide;
In
tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;
1.1: Sharpless dihydroxylation;
DOI:10.1021/ml200254h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 20 h / 20 °C / Inert atmosphere
With
dmap; tetrabutyl ammonium fluoride; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/ml200254h