Technology Process of 4-(2-hydroxymethyl-4,5-dimethoxybenzyl)-5-methyl-4,5,6,7-tetrahydrothieno<3,2-c>pyridine
There total 6 articles about 4-(2-hydroxymethyl-4,5-dimethoxybenzyl)-5-methyl-4,5,6,7-tetrahydrothieno<3,2-c>pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2 h / 140 °C
2: 1.) phosphorus oxychloride, 2.) sodium tetrahydroborate / 1.) ethane nitrile, reflux, 1.5 h, 2.) water/ethanol, 3.5 h
3: 89 percent / potassium carbonate, sulfurous oxychloride / CHCl3 / 3.5 h / Ambient temperature
4: 85 percent / magnesium oxide / tetrahydrofuran; H2O / 2.5 h / 20 °C
With
sodium tetrahydroborate; thionyl chloride; magnesium oxide; potassium carbonate; trichlorophosphate;
In
tetrahydrofuran; chloroform; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2 h / 140 °C
2: 1.) phosphorus oxychloride, 2.) sodium tetrahydroborate / 1.) ethane nitrile, reflux, 1.5 h, 2.) water/ethanol, 3.5 h
3: 89 percent / potassium carbonate, sulfurous oxychloride / CHCl3 / 3.5 h / Ambient temperature
4: 85 percent / magnesium oxide / tetrahydrofuran; H2O / 2.5 h / 20 °C
With
sodium tetrahydroborate; thionyl chloride; magnesium oxide; potassium carbonate; trichlorophosphate;
In
tetrahydrofuran; chloroform; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / magnesium oxide / tetrahydrofuran; H2O / 2.5 h / 20 °C
With
magnesium oxide;
In
tetrahydrofuran; water;
![[2-(2-thyenyl)ethyl]amine](/Databaselist/images/loading.webp)
