Technology Process of (3R,4S,5S,6S)-6-amino-(N-benzyl)-3,4,5-tribenzyloxydodeca-1,11-diene
There total 4 articles about (3R,4S,5S,6S)-6-amino-(N-benzyl)-3,4,5-tribenzyloxydodeca-1,11-diene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium cyanoborohydride; zinc dibromide;
In
tetrahydrofuran; propan-1-ol; water;
for 72h;
Heating;
DOI:10.1016/S0040-4020(01)81779-8
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) Mg / 1) ether, 15 min, 2) ether, 4h, RT
2: 1) oxalyl chloride, DMSO, 2) NEt3 / 1) CH2Cl2, -65 deg C, 15 min, 2) -65 deg C, 5 min
3: 45 percent / NaBH3CN, ZnBr2 / tetrahydrofuran; propan-1-ol; H2O / 72 h / Heating
With
oxalyl dichloride; sodium cyanoborohydride; magnesium; dimethyl sulfoxide; triethylamine; zinc dibromide;
In
tetrahydrofuran; propan-1-ol; water;
DOI:10.1016/S0040-4020(01)81779-8
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) Zn, CeCl3*7H2O, 2) p-TsOH / 1) MeOH, 3h, reflux, 2) acetone, 1.5h, RT
2: 1) Mg / 1) ether, 15 min, 2) ether, 4h, RT
3: 1) oxalyl chloride, DMSO, 2) NEt3 / 1) CH2Cl2, -65 deg C, 15 min, 2) -65 deg C, 5 min
4: 45 percent / NaBH3CN, ZnBr2 / tetrahydrofuran; propan-1-ol; H2O / 72 h / Heating
With
cerium(III) chloride; oxalyl dichloride; sodium cyanoborohydride; toluene-4-sulfonic acid; magnesium; dimethyl sulfoxide; triethylamine; zinc dibromide; zinc;
In
tetrahydrofuran; propan-1-ol; water;
DOI:10.1016/S0040-4020(01)81779-8
