Technology Process of C19H21NO4
There total 11 articles about C19H21NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: AD-mix-α; water; methanesulfonamide / tert-butyl alcohol / 14 h / 0 °C
2.1: pyridine / 3 h / 0 °C
3.1: dimethyl sulfoxide / 16 h / Inert atmosphere
4.1: collidine / dichloromethane / 12 h / 0 °C
5.1: ammonium cerium (IV) nitrate / acetonitrile; water / 0.08 h / 0 °C
6.1: Dess-Martin periodane / dichloromethane / 8 h / 20 °C / Inert atmosphere
7.1: tetrahydrofuran; toluene / 2 h / -78 - 20 °C / Inert atmosphere
8.1: Grubbs catalyst first generation / dichloromethane / 24 h / Inert atmosphere
8.2: 16 h
9.1: 40 h / 20 °C / Inert atmosphere
10.1: toluene-4-sulfonic acid; methanol / 4 h / 20 °C
With
pyridine; Grubbs catalyst first generation; methanol; ammonium cerium (IV) nitrate; methanesulfonamide; AD-mix-α; water; Dess-Martin periodane; toluene-4-sulfonic acid;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol;
1.1: |Sharpless Dihydroxylation / 6.1: |Dess-Martin Oxidation / 9.1: |Diels-Alder Cycloaddition;
DOI:10.1002/ejoc.201301627
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: pyridine / 3 h / 0 °C
2.1: dimethyl sulfoxide / 16 h / Inert atmosphere
3.1: collidine / dichloromethane / 12 h / 0 °C
4.1: ammonium cerium (IV) nitrate / acetonitrile; water / 0.08 h / 0 °C
5.1: Dess-Martin periodane / dichloromethane / 8 h / 20 °C / Inert atmosphere
6.1: tetrahydrofuran; toluene / 2 h / -78 - 20 °C / Inert atmosphere
7.1: Grubbs catalyst first generation / dichloromethane / 24 h / Inert atmosphere
7.2: 16 h
8.1: 40 h / 20 °C / Inert atmosphere
9.1: toluene-4-sulfonic acid; methanol / 4 h / 20 °C
With
pyridine; Grubbs catalyst first generation; methanol; ammonium cerium (IV) nitrate; Dess-Martin periodane; toluene-4-sulfonic acid;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; toluene; acetonitrile;
5.1: |Dess-Martin Oxidation / 8.1: |Diels-Alder Cycloaddition;
DOI:10.1002/ejoc.201301627