C₂₈H₂₃O₅P

Base Information

• Chemical Name: C₂₈H₂₃O₅P
• CAS No.: 1601392-79-3
• Molecular Formula: C₂₈H₂₃O₅P
• Molecular Weight: 470.461
• Mol file: 1601392-79-3.mol

Synonyms:

Chemical Property of C₂₈H₂₃O₅P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₃O₅P

There total 6 articles about C₂₈H₂₃O₅P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Bromo-2-iodobenzene (583-55-1) → C26H21O3P (1601392-77-1) + C28H23O5P (1601392-79-3)

Guidance literature:

Multi-step reaction with 3 steps

1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; 1,3-bis-(diphenylphosphino)propane; N-ethyl-N,N-diisopropylamine / toluene / 96 h / 120 °C / Schlenk technique; Reflux

2: bis(dibenzylideneacetone)-palladium⁽⁰⁾; triphenylphosphine; potassium phosphate / 1,4-dioxane / 12 h / 105 °C / Schlenk technique; Inert atmosphere

3: palladium diacetate / trifluoroacetic acid / 100 °C

With potassium phosphate; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In 1,4-dioxane; toluene; trifluoroacetic acid;

DOI:10.1039/c4cc01238k

Reference yield:

phenylboronic acid (98-80-6) → C26H21O3P (1601392-77-1) + C28H23O5P (1601392-79-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / 1,2-dimethoxyethane; water / 5 h / 80 °C / Inert atmosphere

2.1: n-butyllithium / diethyl ether; hexane / 2 h / 0 °C / Inert atmosphere

2.2: 1 h / 20 °C / Inert atmosphere

3.1: dihydrogen peroxide / methanol; water / 1 h / 20 °C

4.1: palladium diacetate / trifluoroacetic acid / 100 °C

With bis-triphenylphosphine-palladium(II) chloride; n-butyllithium; dihydrogen peroxide; palladium diacetate; potassium carbonate; In methanol; 1,2-dimethoxyethane; diethyl ether; hexane; water; trifluoroacetic acid;

DOI:10.1039/c4cc01238k

Reference yield:

2-Bromobiphenyl (2052-07-5) → C26H21O3P (1601392-77-1) + C28H23O5P (1601392-79-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / diethyl ether; hexane / 2 h / 0 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: dihydrogen peroxide / methanol; water / 1 h / 20 °C

3.1: palladium diacetate / trifluoroacetic acid / 100 °C

With n-butyllithium; dihydrogen peroxide; palladium diacetate; In methanol; diethyl ether; hexane; water; trifluoroacetic acid;

DOI:10.1039/c4cc01238k

upstream raw materials:

phenylboronic acid

(2-bromophenyl)diphenylphosphine oxide

Diphenylphosphine oxide

1-Bromo-2-iodobenzene

Refernces