(2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane

Base Information

• Chemical Name: (2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane
• CAS No.: 88652-74-8
• Molecular Formula: C18H14BrOP
• Molecular Weight: 357.186
• DSSTox Substance ID: DTXSID30522801
• Nikkaji Number: J1.648.029K
• Wikidata: Q82388400
• Mol file: 88652-74-8.mol

Synonyms:88652-74-8;(2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane;SCHEMBL1784097;DTXSID30522801;(2-Bromophenyl)diphenylphosphine oxide;(2-Bromophenyl)diphenyl-phosphine oxide;J-500673

Chemical Property of (2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane

Chemical Property:

• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 355.99656
• Heavy Atom Count: 21
• Complexity: 349

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3Br

Technology Process of (2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane

There total 11 articles about (2-Bromophenyl)(oxo)diphenyl-lambda~5~-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2-bromophenyl)diphenylphosphane (62336-24-7) → (2-bromophenyl)diphenylphosphine oxide (88652-74-8)

Guidance literature:

With dihydrogen peroxide; In methanol; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2004.03.058

Reference yield: 98.0%

1-Bromo-2-iodobenzene (583-55-1) + diphenylphosphane (829-85-6) → (2-bromophenyl)diphenylphosphine oxide (88652-74-8)

Guidance literature:

1-Bromo-2-iodobenzene; diphenylphosphane; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In toluene; at 80 ℃; for 12h; Inert atmosphere;

With dihydrogen peroxide; In tetrahydrofuran; for 3h;

DOI:10.1021/acs.organomet.9b00340

Reference yield: 81.5%

→ (2-bromophenyl)diphenylphosphine oxide (88652-74-8)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; water; for 5h;

upstream raw materials:

furan

lithium diphenylphosphide

2,3-dibromobenzene

2-bromo-1-chlorobenzene

Downstream raw materials:

[1,1′-biphenyl]-2-yldimethylphosphine oxide

2-(2-diphenylphosphinylphenyl)furan

2-(2-diphenylphosphinylphenyl)thiophene

2-(2-diphenylphosphinylphenyl)pyrrole