(Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.0^1,6]tetradeca-7⁽¹⁴⁾,11-diene

Base Information

• Chemical Name: (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.0^1,6]tetradeca-7⁽¹⁴⁾,11-diene
• CAS No.: 116425-14-0
• Molecular Formula: C₃₄H₄₇NOSi
• Molecular Weight: 513.839
• Mol file: 116425-14-0.mol

Synonyms:

Chemical Property of (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.0^1,6]tetradeca-7⁽¹⁴⁾,11-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.0^1,6]tetradeca-7⁽¹⁴⁾,11-diene

There total 4 articles about (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.0^1,6]tetradeca-7⁽¹⁴⁾,11-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C38H52Cl3NO6SSi (116425-13-9) → (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.01,6]tetradeca-7(14),11-diene (116425-14-0)

Guidance literature:

With K-PO₄ buffer; zinc;

DOI:10.1016/S0040-4039(00)96706-6

Reference yield:

1-(t-butyldiphenylsilyloxy)-3-iodopropane (114671-83-9) → (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.01,6]tetradeca-7(14),11-diene (116425-14-0)

Guidance literature:

Multi-step reaction with 3 steps

3: 91 percent / Zn, 1M K-PO₄ buffer

With K-PO₄ buffer; zinc;

DOI:10.1016/S0040-4039(00)96706-6

Reference yield:

C37H48Cl3NO4Si (116425-12-8,116502-02-4) → (Z)-(1R,6R,10R)-10-[3-(tert-Butyl-diphenyl-silanyloxy)-propyl]-9,9-dimethyl-14-aza-tricyclo[5.5.2.01,6]tetradeca-7(14),11-diene (116425-14-0)

Guidance literature:

Multi-step reaction with 2 steps

2: 91 percent / Zn, 1M K-PO₄ buffer

With K-PO₄ buffer; zinc;

DOI:10.1016/S0040-4039(00)96706-6

upstream raw materials:

C₃₈H₅₂Cl₃NO₆SSi

1-(t-butyldiphenylsilyloxy)-3-iodopropane

C₃₇H₄₈Cl₃NO₄Si

tert-butylchlorodiphenylsilane

Downstream raw materials:

C₃₆H₅₂O₃Si