3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-

Base Information

Chemical Name:3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-
CAS No.:1346747-14-5
Molecular Formula:C₂₁H₂₄FN₃O₄
Molecular Weight:401.438
Hs Code.:
Mol file:1346747-14-5.mol

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-

Synonyms:

Suppliers and Price of 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-

Chemical Property:

Boiling Point:636.4±55.0 °C(Predicted)
PKA:6.43±0.50(Predicted)
Density:1.408±0.06 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

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MSDS Files:

Useful:

Uses rel-Moxifloxacin used in the preparation and responsible for antimycobacterial and cytotoxic activity of propylene-triazole-methylene-tethered (thio)semicarbazone-isatin-moxifloxacin hybrids.

Technology Process of 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel-

There total 18 articles about 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-, rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 151213-40-0,158060-81-2,169533-56-6
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With [BCl₂(4-picoline)][AlCl₄]; triethylamine; In methanol; at 85 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior;

Reference yield: 96.0%

: 151213-42-2,158060-81-2,169533-56-6
[R,R]-2,8-diazabicyclo[4.3.0]nonane

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With nano iron oxide on ZrO₂ coated sulfonic acid; In water; for 0.416667h; Reflux;
DOI:10.2174/1570178615666171226162735

Reference yield: 90.0%

: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.; With hydrogenchloride; In methanol; water; at 10 - 15 ℃; for 2h; pH=1.0 - 2.0;

With ammonia; In water; at 25 - 75 ℃; for 1.25h; pH=7.5 - 8; Product distribution / selectivity;