C₂₄H₄₂BNO₂Si₂

Base Information

• Chemical Name: C₂₄H₄₂BNO₂Si₂
• CAS No.: 88824-38-8
• Molecular Formula: C₂₄H₄₂BNO₂Si₂
• Molecular Weight: 443.585
• Mol file: 88824-38-8.mol

Synonyms:

Chemical Property of C₂₄H₄₂BNO₂Si₂

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₂₄H₄₂BNO₂Si₂

There total 1 articles about C₂₄H₄₂BNO₂Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-(1-chloro-2-phenylethyl)boronic acid (1R,2R,3S,5R)-(-)-2,3-pinanediol ester (88824-37-7) + lithium hexamethyldisilazane (4039-32-1) → pinanediol 1-(bis(trimethylsilyl)amino)-2-phenylethane-1-boronate (88824-38-8)

Guidance literature:

In tetrahydrofuran; a soln. of α-chloro ester was cooled to -78°C, treated with LiN(SiMe3)2 in THF, mixt. was stirred overnight at 20-25°C; product was not isolated in pure state;

DOI:10.1021/om00082a019

Reference yield:

pinanediol 1-(bis(trimethylsilyl)amino)-2-phenylethane-1-boronate (88824-38-8) → (-)-pinanediol (S)-1-acetamido-2-phenylethane-1-boronate (88824-39-9)

Guidance literature:

With acetic anhydride; acetic acid; In tetrahydrofuran; a soln. of α-amino ester was cooled to -78°C, treated withan excess of Ac2O followed by glacial AcOH, stirred at 20-25°C for 10-12 h; soln. was concd. under vac., residue chromd. through a short SiO2 column with 5-10% EtOAc-hexane, recrystd. from CH2Cl2 to const. rotation (3 times);

DOI:10.1021/om00082a019

Reference yield:

C24H42BNO2Si2 (132562-16-4,88824-38-8) → C18H26BNO2*ClH

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; pentane; at 0 ℃;

DOI:10.1002/psc.2583

upstream raw materials:

(R)-(1-chloro-2-phenylethyl)boronic acid (1R,2R,3S,5R)-(-)-2,3-pinanediol ester

lithium hexamethyldisilazane

Downstream raw materials:

(-)-pinanediol (S)-1-acetamido-2-phenylethane-1-boronate