{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Base Information

Chemical Name:{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid
CAS No.:199448-96-9
Molecular Formula:C₂₉H₅₀O₉
Molecular Weight:542.711
Hs Code.:

Synonyms:

Suppliers and Price of {2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

There total 15 articles about {2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 199448-95-8
{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid tert-butyl ester

: 199448-96-9
{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Guidance literature:: With trifluoroacetic acid;
DOI:10.1002/anie.199701221

Reference yield:

: 61-90-5,21675-61-6,25248-98-0,70-45-1
L-leucine

: 199448-96-9
{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Guidance literature:: Multi-step reaction with 13 steps

1: 54 percent / aq. NaNO₂, H₂SO₄

2: 75 percent / HCl / toluene

3: 87 percent / TsOH / diethyl ether

4: 94 percent / LiAlH₄ / diethyl ether

5: KOH / tetrahydrofuran

6: TsOH / methanol

7: KOH / tetrahydrofuran

8: TsOH / methanol

9: 90 percent / pyridine

10: 68 percent / KOH / tetrahydrofuran

11: 44 percent / ZnBr₂ / CH₂Cl₂

12: 85 percent / t-BuOK / 2-methyl-propan-2-ol

13: 92 percent / TFA

With pyridine; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; potassium tert-butylate; toluene-4-sulfonic acid; trifluoroacetic acid; zinc dibromide; sodium nitrite; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; tert-butyl alcohol;
DOI:10.1002/anie.199701221

Reference yield:

: 13748-90-8,498-36-2
(S)-2-hydroxyl-3,3-dimethylbutyric acid

: 199448-96-9
{2-[(S)-1-(2-{2-[(S)-1-(2-Benzyloxy-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-ethoxymethyl)-3-methyl-butoxy]-ethoxy}-acetic acid

Guidance literature:: Multi-step reaction with 12 steps

1: 75 percent / HCl / toluene

2: 87 percent / TsOH / diethyl ether

3: 94 percent / LiAlH₄ / diethyl ether

4: KOH / tetrahydrofuran

5: TsOH / methanol

6: KOH / tetrahydrofuran

7: TsOH / methanol

8: 90 percent / pyridine

9: 68 percent / KOH / tetrahydrofuran

10: 44 percent / ZnBr₂ / CH₂Cl₂

11: 85 percent / t-BuOK / 2-methyl-propan-2-ol

12: 92 percent / TFA

With pyridine; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; potassium tert-butylate; toluene-4-sulfonic acid; trifluoroacetic acid; zinc dibromide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; tert-butyl alcohol;
DOI:10.1002/anie.199701221