4-Oxo-4-(quinolin-8-ylamino)butanoic acid

Base Information

• Chemical Name: 4-Oxo-4-(quinolin-8-ylamino)butanoic acid
• CAS No.: 294197-02-7
• Molecular Formula: C₁₃H₁₂N₂O₃
• Molecular Weight: 244.25
• DSSTox Substance ID: DTXSID901273691
• ChEMBL ID: CHEMBL1560505
• Mol file: 294197-02-7.mol

Synonyms:4-oxo-4-(quinolin-8-ylamino)butanoic acid;294197-02-7;N-Quinolin-8-yl-succinamic acid;3-[(quinolin-8-yl)carbamoyl]propanoic acid;4-OXO-4-(8-QUINOLINYLAMINO)BUTANOIC ACID;Oprea1_070543;Oprea1_597270;CBDivE_006354;MLS000714511;n-quinolin-8-ylsuccinamic acid;CHEMBL1560505;SCHEMBL13401554;DTXSID901273691;HMS2692G18;BBL002629;MFCD00440880;STK326059;AKOS000301105;SB68659;SMR000274490;VS-01133;4-oxo-4-(quinolin-8-ylamino)butanoicacid;CS-0316249;F0901-0869

Chemical Property of 4-Oxo-4-(quinolin-8-ylamino)butanoic acid

Chemical Property:

• Boiling Point: 570.5±30.0 °C(Predicted)
• PKA: 4.56±0.10(Predicted)
• Density: 1.376±0.06 g/cm3(Predicted)
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 244.08479225
• Heavy Atom Count: 18
• Complexity: 319

Purity/Quality:

98%min ^*data from raw suppliers

N-Quinolin-8-yl-succinamic acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)NC(=O)CCC(=O)O)N=CC=C2

Technology Process of 4-Oxo-4-(quinolin-8-ylamino)butanoic acid

There total 1 articles about 4-Oxo-4-(quinolin-8-ylamino)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

succinic acid anhydride (108-30-5) + 8-amino quinoline (578-66-5) → 4-(quinolin-8-amino)-4-oxobutanoic acid (294197-02-7)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1002/chem.202002415

upstream raw materials:

succinic acid anhydride

8-amino quinoline