Technology Process of N-<2-(2-ethoxyethoxy)ethyl>-5-<(4,5-diphenyl-1H-imidazol-2-yl)thio>pentanamide
There total 6 articles about N-<2-(2-ethoxyethoxy)ethyl>-5-<(4,5-diphenyl-1H-imidazol-2-yl)thio>pentanamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: aq. K2CO3 / tetrahydrofuran / 4 h / Ambient temperature; 1.) THF,water, RT, 2 h, 2.) THF, water, RT, 4 h
2: 11.4 g / K2CO3, tetra-n-butylammonium iodide / tetrahydrofuran / 2 h / Heating
With
tetra-(n-butyl)ammonium iodide; potassium carbonate;
In
tetrahydrofuran;
DOI:10.1021/jm00007a004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 65 percent / PBr3, pyridine / benzene / 56 h
2: sodium azide, NaI / dimethylformamide / 18 h / 60 °C
3: 1.) Ph3P, 2.) H2O / 1.) THF, RT, 10 h, 2.) THF, RT, 24 h
4: aq. K2CO3 / tetrahydrofuran / 4 h / Ambient temperature; 1.) THF,water, RT, 2 h, 2.) THF, water, RT, 4 h
5: 11.4 g / K2CO3, tetra-n-butylammonium iodide / tetrahydrofuran / 2 h / Heating
With
pyridine; sodium azide; water; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; triphenylphosphine; sodium iodide;
In
tetrahydrofuran; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00007a004
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium azide, NaI / dimethylformamide / 18 h / 60 °C
2: 1.) Ph3P, 2.) H2O / 1.) THF, RT, 10 h, 2.) THF, RT, 24 h
3: aq. K2CO3 / tetrahydrofuran / 4 h / Ambient temperature; 1.) THF,water, RT, 2 h, 2.) THF, water, RT, 4 h
4: 11.4 g / K2CO3, tetra-n-butylammonium iodide / tetrahydrofuran / 2 h / Heating
With
sodium azide; water; tetra-(n-butyl)ammonium iodide; potassium carbonate; triphenylphosphine; sodium iodide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00007a004
