Technology Process of 3-(4-(4-butyryl-3-hydroxy-2-methylphenoxy)butoxy)-2-methylbenzoic acid
There total 5 articles about 3-(4-(4-butyryl-3-hydroxy-2-methylphenoxy)butoxy)-2-methylbenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C24H30O6;
With
potassium hydroxide;
In
1,4-dioxane; water;
for 12h;
Inert atmosphere;
With
hydrogenchloride;
In
1,4-dioxane; dichloromethane; water;
DOI:10.1021/jm5000563
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 6 h / 85 °C / Inert atmosphere
2: potassium carbonate; potassium iodide / acetonitrile / 0.25 h / 160 °C / Inert atmosphere; Microwave irradiation
3: potassium hydroxide / 1,4-dioxane; water / 12 h / Inert atmosphere
With
potassium carbonate; potassium iodide; potassium hydroxide;
In
1,4-dioxane; water; acetonitrile;
DOI:10.1021/jm5000563
- Guidance literature:
-
Multi-step reaction with 3 steps
1: aluminum (III) chloride / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
2: potassium carbonate; potassium iodide / acetonitrile / 0.25 h / 160 °C / Inert atmosphere; Microwave irradiation
3: potassium hydroxide / 1,4-dioxane; water / 12 h / Inert atmosphere
With
aluminum (III) chloride; potassium carbonate; potassium iodide; potassium hydroxide;
In
1,4-dioxane; dichloromethane; water; acetonitrile;
1: |Friedel-Crafts Acylation;
DOI:10.1021/jm5000563
