4-Amino-N-cyclopropylbenzamide

Base Information

Chemical Name:4-Amino-N-cyclopropylbenzamide
CAS No.:38681-77-5
Molecular Formula:C10H12 N2 O
Molecular Weight:176.218
Hs Code.:2924299090
DSSTox Substance ID:DTXSID10191978
Nikkaji Number:J54.640B
Wikidata:Q83064562
Mol file:38681-77-5.mol

Synonyms:4-Amino-N-cyclopropylbenzamide;38681-77-5;N-Cyclopropyl 4-Aminobenzamide;BENZAMIDE, 4-AMINO-N-CYCLOPROPYL-;BRN 2721310;SCHEMBL3442327;4-amino-N-cyclopropyl-benzamide;DTXSID10191978;TZPIKGCQLFRHGR-UHFFFAOYSA-N;BBL017780;MFCD01666630;STK482470;AKOS000264227;LS-25474;VS-06487;BB 0218408;CS-0037913;FT-0678534;EN300-25873;W13126;Z218602490

Suppliers and Price of 4-Amino-N-cyclopropylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cyclopropyl4-Aminobenzamide
250mg
$ 50.00

TRC
N-Cyclopropyl4-Aminobenzamide
100mg
$ 45.00

TRC
N-Cyclopropyl4-Aminobenzamide
500mg
$ 75.00

Matrix Scientific
4-Amino-N-cyclopropylbenzamide
500mg
$ 189.00

Crysdot
4-Amino-N-cyclopropylbenzamide 95+%
25g
$ 914.00

Crysdot
4-Amino-N-cyclopropylbenzamide 95+%
5g
$ 339.00

Crysdot
4-Amino-N-cyclopropylbenzamide 95+%
10g
$ 507.00

Chemenu
4-amino-N-cyclopropylbenzamide 95%
25g
$ 862.00

Chemenu
4-amino-N-cyclopropylbenzamide 95%
10g
$ 479.00

Chemenu
4-amino-N-cyclopropylbenzamide 95%
5g
$ 320.00

Total 12 raw suppliers

Chemical Property of 4-Amino-N-cyclopropylbenzamide

Chemical Property:

Vapor Pressure:8.55E-07mmHg at 25°C
Boiling Point:405.8°C at 760 mmHg
Flash Point:199.2°C
PSA：55.12000
Density:1.2g/cm³
LogP:2.13310
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

N-Cyclopropyl4-Aminobenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1NC(=O)C2=CC=C(C=C2)N

Technology Process of 4-Amino-N-cyclopropylbenzamide

There total 4 articles about 4-Amino-N-cyclopropylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1016680-00-4
tert-butyl (4-((cyclopropyl)carbamoyl)phenyl)carbamate

: 38681-77-5
4-amino-N-cyclopropylbenzamide

Guidance literature:: tert-butyl (4-((cyclopropyl)carbamoyl)phenyl)carbamate; With trifluoroacetic acid; at 25 ℃; for 1h;

With ammonia; In methanol;

Reference yield:

: 66493-39-8
4-(N-tert-butoxycarbonyl)aminobenzoic acid

: 38681-77-5
4-amino-N-cyclopropylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 12 h / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.5b00849

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 38681-77-5
4-amino-N-cyclopropylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / water; 1,4-dioxane / 24 h / 20 °C

2: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

3: trifluoroacetic acid / dichloromethane / 12 h / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.5b00849