Quinoline, 2-[[3-[2-[[2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl]meth yl]-2H-tetrazol-5-yl]phenoxy]methyl]-

Base Information

Chemical Name:Quinoline, 2-[[3-[2-[[2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl]meth yl]-2H-tetrazol-5-yl]phenoxy]methyl]-
CAS No.:138786-29-5
Molecular Formula:C30H28N6O3
Molecular Weight:520.591
Hs Code.:

Synonyms:

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Chemical Property of Quinoline, 2-[[3-[2-[[2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl]meth yl]-2H-tetrazol-5-yl]phenoxy]methyl]-

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Technology Process of Quinoline, 2-[[3-[2-[[2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl]meth yl]-2H-tetrazol-5-yl]phenoxy]methyl]-

There total 5 articles about Quinoline, 2-[[3-[2-[[2-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-6-methoxyphenyl]meth yl]-2H-tetrazol-5-yl]phenoxy]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 78265-34-6
2-<2-(bromomethyl)-3-methoxyphenyl>-4,4-dimethyl-2-oxazoline

: 107813-59-2
2-[3-(2H-Tetrazol-5-yl)-phenoxymethyl]-quinoline

: 138786-29-5
2-<3-methoxy-2-<<5-<3-(quinolin-2-ylmethoxy)phenyl>-2H-tetrazol-2-yl>methyl>phenyl>-4,4-dimethyl-2-oxazoline

Guidance literature:: With potassium carbonate; potassium iodide; In butanone; for 8h; Heating;
DOI:10.1021/jm00085a005

Reference yield:

: 72623-17-7
2-(2-Methyl-3-methoxyphenyl)-4,4-dimethyl-2-oxazoline

: 138786-29-5
2-<3-methoxy-2-<<5-<3-(quinolin-2-ylmethoxy)phenyl>-2H-tetrazol-2-yl>methyl>phenyl>-4,4-dimethyl-2-oxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 3 h / Heating

2: 59 percent / K₂CO₃, KI / butan-2-one / 8 h / Heating

With N-Bromosuccinimide; Perbenzoic acid; potassium carbonate; potassium iodide; In tetrachloromethane; butanone;
DOI:10.1021/jm00085a005

Reference yield:

: 4377-41-7
2-Chloromethylquinoline

: 138786-29-5
2-<3-methoxy-2-<<5-<3-(quinolin-2-ylmethoxy)phenyl>-2H-tetrazol-2-yl>methyl>phenyl>-4,4-dimethyl-2-oxazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, 0.5 h, 2.) DMF, 3 h

2: LiN₃, triethylammonium bromide / 2-methoxy-ethanol / 3 h / 120 °C

3: 59 percent / K₂CO₃, KI / butan-2-one / 8 h / Heating

With lithium azide; triethylamine hydrobromide; sodium hydride; potassium carbonate; potassium iodide; In 2-methoxy-ethanol; butanone;
DOI:10.1021/jm00085a005