(3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride

Base Information

• Chemical Name: (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride
• CAS No.: 70330-57-3
• Molecular Formula: C₂₆H₂₁NO₄P*Cl
• Molecular Weight: 477.884
• Mol file: 70330-57-3.mol

Synonyms:

Chemical Property of (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride

There total 3 articles about (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-nitro-5-chloromethyl-2-hydroxybenzaldehyde (66620-32-4) + triphenylphosphine (603-35-0) → (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride (70330-57-3)

Guidance literature:

In benzene; for 3h; Heating;

DOI:10.1080/00397910701227366

Reference yield:

5-(chloromethyl)salicylaldehyde (23731-06-8) → (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride (70330-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / nitric acid; glacial acetic acid / 30 - 40 °C

2: 91 percent / benzene / 3 h / Heating

With nitric acid; acetic acid; In benzene;

DOI:10.1080/00397910701227366

Reference yield:

salicylaldehyde (90-02-8) → (3-formyl-4-hydroxy-5-nitro-benzyl)-triphenyl-phosphonium; chloride (70330-57-3)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl

2: 78 percent / nitric acid; glacial acetic acid / 30 - 40 °C

3: 91 percent / benzene / 3 h / Heating

With hydrogenchloride; nitric acid; acetic acid; In benzene;

DOI:10.1080/00397910701227366

upstream raw materials:

3-nitro-5-chloromethyl-2-hydroxybenzaldehyde

triphenylphosphine

5-(chloromethyl)salicylaldehyde

salicylaldehyde

Downstream raw materials:

C₁₅H₁₀BrNO₄

C₁₆H₁₀N₂O₄

C₁₆H₁₃NO₅

2-hydroxy-3-nitro-5-styryl-benzaldehyde

Refernces