1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Base Information

Chemical Name:1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate
CAS No.:1280168-05-9
Molecular Formula:C₄₀H₄₉N₉O₈
Molecular Weight:783.885
Hs Code.:

1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Synonyms:

Suppliers and Price of 1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

There total 4 articles about 1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1280168-04-8
1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-ol

: 103-71-9
phenyl isocyanate

: 1280168-05-9
1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Guidance literature:: In tetrahydrofuran; for 48h; Inert atmosphere; Reflux;
DOI:10.1021/jm101493z

Reference yield:

: 22195-47-7,96894-67-6
4-aminomethyl-2,2-dimethyl[1,3]dioxolane

: 1280168-05-9
1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 48 h / 70 °C

2: tetrahydrofuran / 48 h / Reflux

3: tetrahydrofuran / 48 h / Inert atmosphere; Reflux

In tetrahydrofuran;
DOI:10.1021/jm101493z

Reference yield:

: 213840-35-8
2,6-dichloro-N₄,N₈-bis(3,4-dimethoxybenzyl)pyrimido[5,4-d]pyrimidine-4,8-diamine

: 1280168-05-9
1-((4,8-bis((3,4-dimethoxybenzyl)amino)-6-(((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)amino)propan-2-yl phenylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 48 h / 70 °C

2: tetrahydrofuran / 48 h / Reflux

3: tetrahydrofuran / 48 h / Inert atmosphere; Reflux

In tetrahydrofuran;
DOI:10.1021/jm101493z