Adamantane-2β,6α-diol

Base Information

• Chemical Name: Adamantane-2β,6α-diol
• CAS No.: 25106-97-2
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.236
• Mol file: 25106-97-2.mol

Synonyms:

Chemical Property of Adamantane-2β,6α-diol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

adamantane-2,6-diol 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Adamantane-2β,6α-diol

There total 4 articles about Adamantane-2β,6α-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

adamantane-2,6-dione (39751-07-0) → 2,6-dihydroxy-tricyclo<3.3.1.13,7>decane (25106-97-2,76250-83-4,105229-11-6,105307-12-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield: 17.5%

adamantane-2,6-dione (39751-07-0) → 2,6-dihydroxyadamantane (76250-83-4,105307-12-8,25106-97-2)

Guidance literature:

In ethanol; at 30 ℃; for 48h; microbial reduction with Curvularia lunata;

DOI:10.1021/jo00319a022

Reference yield: 11.0%

6-hydroxyadamantan-2-one (67092-78-8) → 2,6-dihydroxyadamantane (76250-83-4,105307-12-8,25106-97-2)

Guidance literature:

at 30 ℃; for 48h; microbial reduction with Curvularia lunata;

DOI:10.1021/jo00319a022

upstream raw materials:

adamantane-2,6-dione

6-hydroxyadamantan-2-one

Downstream raw materials:

(-)-2,6-bis(benzoyloxy)adamantane

(-)-2,6-bis<oxy>adamantane

Refernces

• 1、 Nakazaki, Masao,Chikamatsu, Hiroaki,Nishino, Masayoshi,Murakami, Hiroshi. "Microbial Stereodifferentiating Reduction of 2,6-Adamantanedione and Hexahydrodibenzoheptalene-5,11-dione, Diketones with Two Homotopic Carbonyl Groups on a C2 Symmetry Axis". . p. 1151 - 1156. Retrieved 2007/10/02.