C₁₇H₂₁ClF₃N₃O₂

Base Information

Chemical Name:C₁₇H₂₁ClF₃N₃O₂
CAS No.:1510832-82-2
Molecular Formula:C₁₇H₂₁ClF₃N₃O₂
Molecular Weight:391.821
Hs Code.:

C<sub>17</sub>H<sub>21</sub>ClF<sub>3</sub>N<sub>3</sub>O<sub>2</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₇H₂₁ClF₃N₃O₂

Chemical Property:

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Technology Process of C₁₇H₂₁ClF₃N₃O₂

There total 13 articles about C₁₇H₂₁ClF₃N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1510832-80-0
C₂₆H₃₇ClF₃N₃O₆

: 1510832-82-2
C₁₇H₂₁ClF₃N₃O₂

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethanol; water; at 60 ℃; for 1h;

Reference yield:

: 1268511-99-4,1312798-50-7,1312812-78-4,1523530-23-5,1638759-83-7,454709-92-3,1820579-78-9
tert-butyl (3S,4S)-3-amino-4-hydroxypiperidine-1-carboxylate

: 1510832-82-2
C₁₇H₂₁ClF₃N₃O₂

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / tetrahydrofuran / 1 h / 0 °C

2: sodium hydride / tetrahydrofuran / 4 h / 0 - 20 °C

3: sodium hydride / tetrahydrofuran / 2 h

4: chloro-trimethyl-silane; iodine; N,N,N,N,-tetramethylethylenediamine / toluene / 4 h / 0 - 20 °C

5: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C

6: hydrogenchloride / ethanol; 1,4-dioxane; water / 1 h / 60 °C

With hydrogenchloride; chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; iodine; sodium hydride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; ethanol; water; toluene;

Reference yield:

: 1510866-72-4
(3S,4S)-3-aminopiperidin-4-ol

: 1510832-82-2
C₁₇H₂₁ClF₃N₃O₂

Guidance literature:: Multi-step reaction with 8 steps

1: 12 h

2: triethylamine / tetrahydrofuran / 4 h / 20 °C

3: triethylamine / tetrahydrofuran / 1 h / 0 °C

4: sodium hydride / tetrahydrofuran / 4 h / 0 - 20 °C

5: sodium hydride / tetrahydrofuran / 2 h

6: chloro-trimethyl-silane; iodine; N,N,N,N,-tetramethylethylenediamine / toluene / 4 h / 0 - 20 °C

7: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C

8: hydrogenchloride / ethanol; 1,4-dioxane; water / 1 h / 60 °C

With hydrogenchloride; chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; iodine; sodium hydride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; ethanol; water; toluene;