Azilsartan Impurity

Base Information

Chemical Name:Azilsartan Impurity
CAS No.:1675221-59-6
Molecular Formula:C₂₅H₂₂N₂O₅
Molecular Weight:430.46
Hs Code.:

Synonyms:

Suppliers and Price of Azilsartan Impurity

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of Azilsartan Impurity

Chemical Property:

Boiling Point:627.7±65.0 °C(Predicted)
PKA:3.82±0.36(Predicted)
Density:1.26±0.1 g/cm3(Predicted)

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Azilsartan Impurity

There total 2 articles about Azilsartan Impurity which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139481-44-0
methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-benzimidazole-7-carboxylate

: 1675221-59-6
C₂₅H₂₂N₂O₅

: 147403-65-4
methyl 2-ethoxy-1-((2′-(N′-hydroxycarbamimidoyl)-biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

Guidance literature:: methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-benzimidazole-7-carboxylate; With hydroxylamine hydrochloride; sodium hydrogencarbonate; In dimethyl sulfoxide; at 95 - 100 ℃;

With water; In dimethyl sulfoxide; at 20 - 25 ℃; Overall yield = 54 %;
DOI:10.1021/op500357r

Reference yield:

: 139481-44-0
methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-benzimidazole-7-carboxylate

: 147404-76-0
methyl 1-[(2'-carbamoylbiphenyl-4-yl)methyl]-2-ethoxybenzimidazole-7-carboxylate

: 1675221-59-6
C₂₅H₂₂N₂O₅

: 147403-65-4
methyl 2-ethoxy-1-((2′-(N′-hydroxycarbamimidoyl)-biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

Guidance literature:: methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-benzimidazole-7-carboxylate; With hydroxylamine hydrochloride; sodium hydrogencarbonate; In dimethyl sulfoxide; at 80 - 85 ℃;

With water; In dimethyl sulfoxide; at 20 - 25 ℃; Overall yield = 55 %;
DOI:10.1021/op500357r