1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane

Base Information

• Chemical Name: 1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane
• CAS No.: 2356-61-8
• Molecular Formula: C3H F7 O
• Molecular Weight: 186.029
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID10896471
• Nikkaji Number: J665.424J
• Wikidata: Q82872859
• Mol file: 2356-61-8.mol

Synonyms:1,1,2,2-tetrafluoro-1-(trifluoromethoxy)ethane;2356-61-8;SCHEMBL892307;DTXSID10896471;MEVYDFZGEHEVSM-UHFFFAOYSA-N

Chemical Property of 1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane

Chemical Property:

• Vapor Pressure: 2716.607mmHg at 25°C
• Melting Point: -141.15°C
• Refractive Index: 1.3527 (estimate)
• Boiling Point: -12.105°C at 760 mmHg
• Flash Point: -49.379°C
• PSA: 9.23000
• Density: 1.512g/cm³
• LogP: 2.38070
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 185.99156179
• Heavy Atom Count: 11
• Complexity: 126

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(OC(F)(F)F)(F)F)(F)F

Technology Process of 1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane

There total 2 articles about 1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

sodium perfluoro-β-methoxypropionate (24499-36-3) → trifluoromethyl-1H-pentafluoroethyl ether (2356-61-8) + trifluoromethyl trifluorovinyl ether (1187-93-5)

Guidance literature:

With sodium hydroxide; at 175 - 345 ℃;

Reference yield:

hypofluorous acid trifluoromethyl ester (373-91-1) + 1,2-dichloro-1,2-difluoroethene (598-88-9) + 1,1,2-trifluoroethylene (359-11-5) → 1,2,2,2-Tetrafluoroethyl trifluoromethyl ether (2356-62-9) + trifluoromethyl-1H-pentafluoroethyl ether (2356-61-8) + 1-trifluoromethoxy-1,2-dichlorotrifluoroethane (2356-53-8)

Guidance literature:

In trichlorofluoromethane; at -105 ℃; Rate constant; Product distribution; competition with ClFC=CFCl and FHC=CF₂, relative addition rates and orientation ratios;

DOI:10.1021/jo00125a033

upstream raw materials:

sodium perfluoro-β-methoxypropionate

hypofluorous acid trifluoromethyl ester

1,2-dichloro-1,2-difluoroethene

1,1,2-trifluoroethylene