Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester

Base Information

• Chemical Name: Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester
• CAS No.: 136055-04-4
• Molecular Formula: C₄₃H₅₁NO₁₃S₂
• Molecular Weight: 854.009
• Mol file: 136055-04-4.mol

Synonyms:

Chemical Property of Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester

There total 5 articles about Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[2-(chloroethoxy)ethoxy]ethanol (5197-62-6) → Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester (136055-04-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 86 percent / NaI, NaHCO₃ / acetone / 60 °C

2: 87 percent / NaSH / methanol / 3 h / Ambient temperature

3: 85 percent / dil. NH₃, O₂ / 48 h / pH 8

4: 83 percent / pyridine / 2 h / Ambient temperature

5: 4-dimethylaminopyridine, pyridine

6: pyridine, DCCD / dioxane

With pyridine; dmap; ammonium hydroxide; sodium hydrogensulfide; oxygen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; sodium iodide; In 1,4-dioxane; methanol; acetone;

DOI:10.1016/S0040-4020(01)90786-0

Reference yield:

2-[2-(2-iodoethoxy)ethoxy]ethanol (62573-16-4) → Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester (136055-04-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 87 percent / NaSH / methanol / 3 h / Ambient temperature

2: 85 percent / dil. NH₃, O₂ / 48 h / pH 8

3: 83 percent / pyridine / 2 h / Ambient temperature

4: 4-dimethylaminopyridine, pyridine

5: pyridine, DCCD / dioxane

With pyridine; dmap; ammonium hydroxide; sodium hydrogensulfide; oxygen; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol;

DOI:10.1016/S0040-4020(01)90786-0

Reference yield:

2-<2-(2-mercaptoethoxy)ethoxy>ethanol (56282-36-1) → Succinic acid 2-(2-{2-[2-(2-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethoxy}-ethoxy)-ethyldisulfanyl]-ethoxy}-ethoxy)-ethyl ester 4-nitro-phenyl ester (136055-04-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / dil. NH₃, O₂ / 48 h / pH 8

2: 83 percent / pyridine / 2 h / Ambient temperature

3: 4-dimethylaminopyridine, pyridine

4: pyridine, DCCD / dioxane

With pyridine; dmap; ammonium hydroxide; oxygen; dicyclohexyl-carbodiimide; In 1,4-dioxane;

DOI:10.1016/S0040-4020(01)90786-0

upstream raw materials:

2-[2-(chloroethoxy)ethoxy]ethanol

2-[2-(2-iodoethoxy)ethoxy]ethanol

2-<2-(2-mercaptoethoxy)ethoxy>ethanol

ω,ω'-dithiodi<2-<2-(2-ethoxy)ethoxy>ethanol>