Technology Process of methyl 2-acetamido-4-O-acetyl-6-O-benzyl-2-deoxy-3-O-(2,3,4-tri-O-benzyl-α-L-idopyranosyl)-β-D-galactopyranoside
There total 13 articles about methyl 2-acetamido-4-O-acetyl-6-O-benzyl-2-deoxy-3-O-(2,3,4-tri-O-benzyl-α-L-idopyranosyl)-β-D-galactopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 61 percent / toluene-p-sulfonic acid monohydrate / 5 h / Ambient temperature
2: 97 percent / pyridine
3: 1) sodium hydride 2) 90 percent aq. trifluoroacetic acid / 1) N,N-dimethylformamid, stirred for 1 h 2) room temp., 10 min.
4: toluene-p-sulfonic acid monohydrate 2) 80 percent aq. acetic acid / 1) toluene, room temp., 1 h 2) room temp., 10 min.
6: 4 percent nickel dichloride hexahydrate, 2 percent boric acid, sodium borohydride / ethanol; tetrahydrofuran
7: M sodium hydroxyde / methanol / 0.25 h
With
pyridine; sodium hydroxide; sodium tetrahydroborate; boric acid; sodium hydride; toluene-4-sulfonic acid; acetic acid; trifluoroacetic acid; nickel dichloride;
toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; ethanol;
DOI:10.1016/S0008-6215(00)90218-0
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 60 percent / M sodium methoxyde / 1 h / Ambient temperature
2: 61 percent / toluene-p-sulfonic acid monohydrate / 5 h / Ambient temperature
3: 97 percent / pyridine
4: 1) sodium hydride 2) 90 percent aq. trifluoroacetic acid / 1) N,N-dimethylformamid, stirred for 1 h 2) room temp., 10 min.
5: toluene-p-sulfonic acid monohydrate 2) 80 percent aq. acetic acid / 1) toluene, room temp., 1 h 2) room temp., 10 min.
7: 4 percent nickel dichloride hexahydrate, 2 percent boric acid, sodium borohydride / ethanol; tetrahydrofuran
8: M sodium hydroxyde / methanol / 0.25 h
With
pyridine; sodium hydroxide; sodium tetrahydroborate; sodium methylate; boric acid; sodium hydride; toluene-4-sulfonic acid; acetic acid; trifluoroacetic acid; nickel dichloride;
toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; ethanol;
DOI:10.1016/S0008-6215(00)90218-0
- Guidance literature:
-
Multi-step reaction with 4 steps
1: toluene-p-sulfonic acid monohydrate 2) 80 percent aq. acetic acid / 1) toluene, room temp., 1 h 2) room temp., 10 min.
3: 4 percent nickel dichloride hexahydrate, 2 percent boric acid, sodium borohydride / ethanol; tetrahydrofuran
4: M sodium hydroxyde / methanol / 0.25 h
With
sodium hydroxide; sodium tetrahydroborate; boric acid; toluene-4-sulfonic acid; acetic acid; nickel dichloride;
In
tetrahydrofuran; methanol; ethanol;
DOI:10.1016/S0008-6215(00)90218-0
