C₁₈H₂₁NO₆

Base Information

• Chemical Name: C₁₈H₂₁NO₆
• CAS No.: 1314030-34-6
• Molecular Formula: C₁₈H₂₁NO₆
• Molecular Weight: 347.368
• Mol file: 1314030-34-6.mol

Synonyms:

Chemical Property of C₁₈H₂₁NO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₈H₂₁NO₆

There total 1 articles about C₁₈H₂₁NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cycl-isopropylidene malonate (2033-24-1) + BOC-L-aspartic acid 4-benzyl ester (7536-58-5,98482-77-0) → C18H21NO6 (1314030-34-6)

Guidance literature:

cycl-isopropylidene malonate; BOC-L-aspartic acid 4-benzyl ester; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 25 ℃; for 14h; Inert atmosphere;

In dichloromethane; ethyl acetate; for 0.5h; Inert atmosphere; Reflux;

DOI:10.1021/ja2033734

Reference yield:

C18H21NO6 (1314030-34-6) → (S)-benzyl 2-(3,5-dioxopyrrolidin-2-yl)acetate (1316848-20-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ja2033734

Reference yield:

C18H21NO6 (1314030-34-6) + o-aminobenzaldehyde (529-23-7) → C20H16N2O3 (1314030-40-4)

Guidance literature:

In acetic acid; at 120 ℃; for 0.166667h; Inert atmosphere; Microwave irradiation;

DOI:10.3998/ark.5550190.0012.923

upstream raw materials:

cycl-isopropylidene malonate

BOC-L-aspartic acid 4-benzyl ester

Downstream raw materials:

C₂₀H₁₆N₂O₃

(S)-benzyl 2-(3,5-dioxopyrrolidin-2-yl)acetate

benzyl 2-((S)-3-((S)-3-((S)-3-(tert-butoxy)-2-((S)-sec-butyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)pyrrolidin-1-yl)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)acetate