3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-

Base Information

Chemical Name:3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-
CAS No.:188534-07-8
Molecular Formula:C₁₆H₁₄FNO₂
Molecular Weight:271.291
Hs Code.:
DSSTox Substance ID:DTXSID90444479

Synonyms:188534-07-8;3-BUTYN-2-AMINE, 4-[3-(4-FLUOROPHENOXY)PHENYL]-N-HYDROXY-;SCHEMBL8198208;DTXSID90444479;XZBWTHMHIYVMLH-UHFFFAOYSA-N;N-[4-(3-(4-fluorophenoxy)phenyl)-3-butyn-2-yl]hydroxylamine

Suppliers and Price of 3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:271.10085685
Heavy Atom Count:20
Complexity:354

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C#CC1=CC(=CC=C1)OC2=CC=C(C=C2)F)NO

Technology Process of 3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-

There total 2 articles about 3-Butyn-2-amine, 4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₆H₃₀FNO₆

: 188534-07-8
N-[4-(3-(4-fluorophenoxy)phenyl)-3-butyn-2-yl]hydroxylamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 0.5h; Ambient temperature;
DOI:10.1021/jm9700474

Reference yield:

: 188534-03-4
4-[3-(4-fluorophenoxy)phenyl]-3-butyn-2-ol

: 188534-07-8
N-[4-(3-(4-fluorophenoxy)phenyl)-3-butyn-2-yl]hydroxylamine

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine, diisopropyl azodicarboxylate / tetrahydrofuran / 0.5 h / Ambient temperature

2: TFA / CH₂Cl₂ / 0.5 h / Ambient temperature

With di-isopropyl azodicarboxylate; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm9700474