6,7-diethoxy-1-veratryl-isoquinoline

Base Information

• Chemical Name: 6,7-diethoxy-1-veratryl-isoquinoline
• CAS No.: 102663-69-4
• Molecular Formula: C₂₂H₂₅NO₄
• Molecular Weight: 367.445
• Mol file: 102663-69-4.mol

Synonyms:

Chemical Property of 6,7-diethoxy-1-veratryl-isoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-diethoxy-1-veratryl-isoquinoline

There total 6 articles about 6,7-diethoxy-1-veratryl-isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3,4-dimethoxy-phenyl)-acetic acid-(3,4-diethoxy-phenethylamide) → 6,7-diethoxy-1-veratryl-isoquinoline (102663-69-4)

Guidance literature:

With trichlorophosphate; benzene; unter Stickstoff und anschliessenden Erhitzen des Reaktionsprodukts mit Palladium/Kohle in Decalin auf 184-196grad;

DOI:10.1021/ja01166a009

Reference yield:

(3,4-Dimethoxyphenyl)acetic acid (93-40-3) → 6,7-diethoxy-1-veratryl-isoquinoline (102663-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 200 °C

2: phosphoryl chloride; benzene / unter Stickstoff und anschliessenden Erhitzen des Reaktionsprodukts mit Palladium/Kohle in Decalin auf 184-196grad

With trichlorophosphate; benzene;

DOI:10.1021/ja01166a009

Reference yield:

3,4-diethoxyphenylacetonitrile (27472-21-5) → 6,7-diethoxy-1-veratryl-isoquinoline (102663-69-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Raney nickel; ethanolic NH₃ / 120 - 140 °C / 91938.4 Torr / Hydrogenation

2: 200 °C

3: phosphoryl chloride; benzene / unter Stickstoff und anschliessenden Erhitzen des Reaktionsprodukts mit Palladium/Kohle in Decalin auf 184-196grad

With ammonia; nickel; trichlorophosphate; benzene;

DOI:10.1021/ja01166a009

upstream raw materials:

(3,4-Dimethoxyphenyl)acetic acid

3,4-diethoxyphenylacetonitrile

2-(3,4-diethoxyphenyl)ethylamine