Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)-

Base Information

Chemical Name:Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)-
CAS No.:114990-93-1
Molecular Formula:C₁₀H₁₁FO₃
Molecular Weight:198.194
Hs Code.:
Mol file:114990-93-1.mol

Synonyms:

Suppliers and Price of Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(ALPHAR)-ALPHA-HYDROXY-4-FLUORO-BENZENEBUTANOIC ACID 95.00%
5MG
$ 500.54

Total 1 raw suppliers

Chemical Property of Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)-

Chemical Property:

Purity/Quality:: (ALPHAR)-ALPHA-HYDROXY-4-FLUORO-BENZENEBUTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)-

There total 22 articles about Benzenebutanoic acid, 4-fluoro-.alpha.-hydroxy-, (.alpha.R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 225233-79-4
rac-2-amino-4-(4-fluorophenyl)butanoic acid

: 917247-89-3,114990-93-1
rac-2-hydroxy-4-(4-fluorophenyl)butanoic acid

Guidance literature:: With sulfuric acid; sodium nitrite; at 0 - 20 ℃;
DOI:10.1002/ejoc.200600454

Reference yield:

: 1267352-87-3
C₁₀H₉FO₃

: 114990-93-1
(R)-2-hydroxy-4-(4-fluorophenyl)butanoic acid

: 114990-93-1
(S)-2-hydroxy-4-(4-fluorophenyl)butanoic acid

Guidance literature:: With [RuCl(benzene){(2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine)}]Cl; hydrogen bromide; hydrogen; In tetrahydrofuran; water; at 70 ℃; for 20h; under 20686.5 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1016/j.tet.2011.06.071

Reference yield:

: 1267352-87-3
C₁₀H₉FO₃

: 114990-93-1
(R)-2-hydroxy-4-(4-fluorophenyl)butanoic acid

: 114990-93-1
(S)-2-hydroxy-4-(4-fluorophenyl)butanoic acid

Guidance literature:: With [RuCl(benzene){(2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine)}]Cl; hydrogen bromide; hydrogen; In tetrahydrofuran; water; at 70 ℃; for 20h; under 20686.5 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1016/j.tet.2011.06.071