C₂₀H₂₈N₂O₃

Base Information

Chemical Name:C₂₀H₂₈N₂O₃
CAS No.:1334482-99-3
Molecular Formula:C₂₀H₂₈N₂O₃
Molecular Weight:344.454
Hs Code.:

C<sub>20</sub>H<sub>28</sub>N<sub>2</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₂₈N₂O₃

Chemical Property:

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Technology Process of C₂₀H₂₈N₂O₃

There total 8 articles about C₂₀H₂₈N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₂H₃₉N₂O₇P

: 1334482-99-3
C₂₀H₂₈N₂O₃

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; hexane; at 0 - 10 ℃; for 3.5h; Inert atmosphere; Large scale reaction;
DOI:10.1021/op2001854

Reference yield:

: 1334483-06-5
(7R,9aS)-tert-butyl 2-benzoyloctahydro-1H-pyrido[1,2-a]-pyrazine-7-carboxylate D-tartrate

: 1334482-99-3
C₂₀H₂₈N₂O₃

Guidance literature:: With sodium hydroxide; In tert-butyl methyl ether; water; at 15 - 22 ℃; for 1.75h; Inert atmosphere; Large scale reaction;
DOI:10.1021/op2001854

Reference yield:

: 660862-47-5
(S)-2-(piperazin-2-yl)ethan-1-ol

: 1334482-99-3
C₂₀H₂₈N₂O₃

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / 65 - 75 °C / Inert atmosphere; Large scale reaction

1.2: 4 h / 20 °C / Inert atmosphere; Large scale reaction

2.1: tetrahydrofuran / 48 h / 50 - 60 °C / Inert atmosphere; Large scale reaction

3.1: triethylamine / toluene / 16 h / 0 - 25 °C / Inert atmosphere; Large scale reaction

4.1: lithium hexamethyldisilazane / tetrahydrofuran; hexane / 3.5 h / 0 - 10 °C / Inert atmosphere; Large scale reaction

With triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; hexane; toluene; 2.1: Michael addition;
DOI:10.1021/op2001854