Technology Process of C22H16Cl2F3NO3
There total 10 articles about C22H16Cl2F3NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C23H18Cl2F3NO3;
With
sodium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 20 ℃;
DOI:10.1016/j.cclet.2010.11.008
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: aluminum (III) chloride / 2.5 h / 160 - 250 °C / Inert atmosphere
2.1: water; sodium hydroxide / 2 h / Reflux
3.1: toluene-4-sulfonic acid / 3 h / 80 °C
4.1: triphenylphosphine; diethylazodicarboxylate / diethyl ether / 20 °C
5.1: sodium hydroxide / tetrahydrofuran / 20 °C
5.2: 20 °C
With
aluminum (III) chloride; water; toluene-4-sulfonic acid; triphenylphosphine; sodium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; diethyl ether;
4.1: Mitsunobu reaction;
DOI:10.1016/j.cclet.2010.11.008
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: water; sodium hydroxide / 2 h / Reflux
2.1: toluene-4-sulfonic acid / 3 h / 80 °C
3.1: triphenylphosphine; diethylazodicarboxylate / diethyl ether / 20 °C
4.1: sodium hydroxide / tetrahydrofuran / 20 °C
4.2: 20 °C
With
water; toluene-4-sulfonic acid; triphenylphosphine; sodium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; diethyl ether;
3.1: Mitsunobu reaction;
DOI:10.1016/j.cclet.2010.11.008
