2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate

Base Information

• Chemical Name: 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate
• CAS No.: 87423-04-9
• Molecular Formula: C₆H₅O₃S*C₁₄H₁₀N₃OS₃
• Molecular Weight: 489.621
• Mol file: 87423-04-9.mol

Synonyms:

Chemical Property of 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate

There total 1 articles about 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

4-chloro-2-oxo-2,3-dihydrothiazole-5-carbaldehyde (55359-96-1) + 4-amino-2-methylthio-5-phenylthiazolium benzenesulfonate (82646-26-2) → 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate (87423-04-9)

Guidance literature:

In acetic acid; at 100 ℃; for 1h;

DOI:10.1007/BF00506102

Reference yield: 71.0%

3-ethyl-2-methylbenzothiazolium p-toluenesulfonate (14933-76-7) + 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate (87423-04-9) → 6-Phenyl-8-<(3-ethyl-2-benzothiazolinylidene)methyl>thiazolo<3,4-a>thiazolo<5,4-e>pyrimidinium 2-oxide (87423-06-1)

Guidance literature:

1) EtOH-DMF, reflux; 2) Et₃N;

DOI:10.1007/BF00506102

Reference yield: 55.0%

2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate (87423-04-9) + 4-methyl-1-ethylquinolinium perchlorate → 6-Phenyl-8-<(1-ethyl-1,4-dihydroquinolin-4-ylidene)methyl>thiazolo<3,4-a>thiazolo<5,4-e>pyrimidinium 2-oxide (87423-07-2)

Guidance literature:

1) EtOH-DMF, reflux; 2) Et₃N;

DOI:10.1007/BF00506102

upstream raw materials:

4-chloro-2-oxo-2,3-dihydrothiazole-5-carbaldehyde

4-amino-2-methylthio-5-phenylthiazolium benzenesulfonate

Downstream raw materials:

6-Phenyl-8-<(3-ethyl-2-benzothiazolinylidene)methyl>thiazolo<3,4-a>thiazolo<5,4-e>pyrimidinium 2-oxide

6-Phenyl-8-<(1-ethyl-1,4-dihydroquinolin-4-ylidene)methyl>thiazolo<3,4-a>thiazolo<5,4-e>pyrimidinium 2-oxide