3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Base Information

Chemical Name:3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine
CAS No.:129835-20-7
Molecular Formula:C₂₅H₄₄N₅O₇PSi
Molecular Weight:585.713
Hs Code.:

3'-O-(tert-butyldimethylsilyl)-5'-O-<<bis(2,2-dimethyl-1-aziridinyl)phosphinyl>carbamoyl>thymidine

Synonyms:

Suppliers and Price of 3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

There total 5 articles about 3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2658-24-4
2,2-dimethylaziridine

: 129848-69-7
3'-O-(tert-butyldimethylsilyl)-5'-O-<(dichlorophosphinyl)carbamoyl>thymidine

: 129835-20-7
3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 5 ℃; for 22h;
DOI:10.1021/jm00171a039

Reference yield:

: 64722-98-1
1-{(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione

: 129835-20-7
3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Guidance literature:: Multi-step reaction with 3 steps

1: 80percent acetic acid / 3 h / Ambient temperature

2: tetrahydrofuran / 4 h / 0.5 °C

3: Et₃N / tetrahydrofuran / 22 h / 0 - 5 °C

With acetic acid; triethylamine; In tetrahydrofuran;
DOI:10.1021/jm00171a039

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 129835-20-7
3'-O-(tert-butyldimethylsilyl)-5'-O-<carbamoyl>thymidine

Guidance literature:: Multi-step reaction with 4 steps

1: imidazole / dimethylformamide / 3 h / Ambient temperature

2: 80percent acetic acid / 3 h / Ambient temperature

3: tetrahydrofuran / 4 h / 0.5 °C

4: Et₃N / tetrahydrofuran / 22 h / 0 - 5 °C

With 1H-imidazole; acetic acid; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00171a039