ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate

Base Information

• Chemical Name: ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate
• CAS No.: 26823-07-4
• Molecular Formula: C₁₆H₂₀O₄
• Molecular Weight: 276.332
• Mol file: 26823-07-4.mol

Synonyms:

Chemical Property of ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate

There total 5 articles about ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 6,6-ethylenedioxy-6-phenyl-2,2-dimethyl-3-oxohexanoate (77613-73-1) → ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate (26823-07-4)

Guidance literature:

With sulfuric acid; In methanol; water; for 720h; Yield given; Ambient temperature;

Reference yield:

ethyl 2-bromoisobutyrate (600-00-0) → ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate (26823-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / Zn / benzene; diethyl ether / 6 h / Heating

2: 8N H₂SO₄ / methanol; H₂O / 720 h / Ambient temperature

With sulfuric acid; zinc; In methanol; diethyl ether; water; benzene;

Reference yield:

2-(2-ethoxycarbonylethyl)-2-phenyl-1,3-dioxolane (17851-55-7) → ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate (26823-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / Zn / benzene; diethyl ether / 6 h / Heating

2: 8N H₂SO₄ / methanol; H₂O / 720 h / Ambient temperature

With sulfuric acid; zinc; In methanol; diethyl ether; water; benzene;

upstream raw materials:

ethyl 2-bromoisobutyrate

2-(2-ethoxycarbonylethyl)-2-phenyl-1,3-dioxolane

3-(2-phenyl-[1,3]dioxolan-2-yl)-propionitrile

ethyl 6,6-ethylenedioxy-6-phenyl-2,2-dimethyl-3-oxohexanoate

Downstream raw materials:

1-phenyl-5-methyl-1,4-hexanedione

2-iso-propyl-5-phenylfuran