17851-55-7

Upstream product

• 6270-17-3 ethyl 3-benzoylpropanoate 
• 107-21-1 ethylene glycol 

Downstream Products

• 6938-44-9 ethyl 2-methyl-4-oxo-4-phenyl-butanoate 
• 77613-77-5 ethyl 3-hydroxy-6,6-ethylenedioxy-6-phenyl-2,2-dimethylhexanoate 
• 77613-86-6 2,2-dimethyl-2-(5'-methoxy-5'-phenyl-2'-tetrahydrofuryl)ethyl mesylate 
• 77613-81-1 ethyl 2-(5'methoxy-5'-phenyl-2'-tetrahydrofuryl)isobutyrate 
• 77613-78-6 2,2-Dimethyl-5-(2-phenyl-[1,3]dioxolan-2-yl)-pentane-1,3-diol 
• 77613-75-3 6,6-ethylenedioxy-6-phenyl-2-methylhexan-3-ol 
• 77613-74-2 6,6-ethylenedioxy-6-phenyl-2-methylhexan-3-one 
• 77613-82-2 2,2-dimethyl-2-(5'-methoxy-5'-phenyl-2'-tetrahydrofuryl)-ethanol 
• 77613-83-3 4,4-Dimethyl-1-phenyl-2,8-dioxa-bicyclo[3.2.1]octane 
• 77613-76-4 4-hydroxy-1-phenyl-5-methylhexan-1-one 
• 26823-07-4 ethyl 6-phenyl-2,2-dimethyl-3,6-dioxohexanoate 
• 26823-15-4 1-phenyl-5-methyl-1,4-hexanedione 
• 58509-74-3 2-iso-propyl-5-phenylfuran 
• 353460-44-3 (E)-ethyl 6-oxo-6-phenyl-2-hexenoate 

Relevant academic research and scientific papers

The First Tandem [2 + 2] Cycloaddition-Michael Reaction Using Ynolates: Facile Construction of Substituted Carbocycles

(matrix presented) A tandem [2 + 2] cycloaddition-Michael reaction using ynolate anions followed by decarboxylation produced polysubstituted five-, six-, and seven-membered cycloalkenes.

REACTIONS RELATED TO COENZYME B12 DEPENDENT REARRANGEMENTS: METAL MEDIATED FREE RADICAL ACYL MIGRATIONS IN METHYL AND CYCLOPROPYL SUBSTITUTED MODELS

Free radicals generated from the methylmalonylcoenzyme A mutase model substrates (3) and (4) by chromium(II) reduction, or by pyrolysis of the analogous cobaloximes, underwent -migration only in the acyl series (R=Ph, Me) and not the critical ester series (R=OEt, SBu).The mechanism of the migration was implied by incorporation into (4) of the cyclopropyl ring, the opening of which demonstrated the free radical nature of rearranged intermediate.