4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Base Information

Chemical Name:4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester
CAS No.:80235-27-4
Molecular Formula:C₃₉H₄₇ClN₅O₁₃P
Molecular Weight:860.255
Hs Code.:

4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Synonyms:

Suppliers and Price of 4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

There total 3 articles about 4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 60943-91-1
N⁶-(4-methoxy-benzoyl)-O^2'-(4-methoxy-tetrahydro-pyran-4-yl)-adenosine

: 80235-27-4
4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / 2-chloro-1-methylpyridinium iodide, 1,4-diazabicyclo<2.2.2>octane / acetonitrile; dioxane / 2 h

2: 1.) 1-methylimidazole; 2.) pyridine, water / 1.) acetonitrile; 2.) 30 min

3: 2,4,6-triisopropylbenzenesulphonic acid, zinc / pyridine / 5-10 sec, 35 deg C, 1 min

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; 1-methyl-1H-imidazole; 2,4,6-tri(iso-propyl)benzenesulfonic acid; 2-chloro-1-methyl-pyridinium iodide; water; zinc; In 1,4-dioxane; pyridine; acetonitrile;

Reference yield:

: 123-76-2
levulinic acid

: 80235-27-4
4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / 2-chloro-1-methylpyridinium iodide, 1,4-diazabicyclo<2.2.2>octane / acetonitrile; dioxane / 2 h

2: 1.) 1-methylimidazole; 2.) pyridine, water / 1.) acetonitrile; 2.) 30 min

3: 2,4,6-triisopropylbenzenesulphonic acid, zinc / pyridine / 5-10 sec, 35 deg C, 1 min

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; 1-methyl-1H-imidazole; 2,4,6-tri(iso-propyl)benzenesulfonic acid; 2-chloro-1-methyl-pyridinium iodide; water; zinc; In 1,4-dioxane; pyridine; acetonitrile;

Reference yield:

: 69497-76-3
4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-hydroxy-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

: 80235-27-4
4-Oxo-pentanoic acid (2R,3R,4R,5R)-3-[(4-tert-butyl-2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[6-(4-methoxy-benzoylamino)-purin-9-yl]-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 1-methylimidazole; 2.) pyridine, water / 1.) acetonitrile; 2.) 30 min

2: 2,4,6-triisopropylbenzenesulphonic acid, zinc / pyridine / 5-10 sec, 35 deg C, 1 min

With pyridine; 1-methyl-1H-imidazole; 2,4,6-tri(iso-propyl)benzenesulfonic acid; water; zinc; In pyridine;