23-phenyl-24-nor-5β-cholanone-(23)

Base Information

• Chemical Name: 23-phenyl-24-nor-5β-cholanone-(23)
• CAS No.: 55542-01-3
• Molecular Formula: C₂₉H₄₂O
• Molecular Weight: 406.652
• Mol file: 55542-01-3.mol

Synonyms:

Chemical Property of 23-phenyl-24-nor-5β-cholanone-(23)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 23-phenyl-24-nor-5β-cholanone-(23)

There total 10 articles about 23-phenyl-24-nor-5β-cholanone-(23) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-1,2-diphenyl-pentan-1-one → 23-phenyl-24-nor-5β-cholanone-(23) (55542-01-3)

Guidance literature:

With potassium tert-butylate; oxygen; In tert-butyl alcohol;

DOI:10.1016/S0040-4020(01)97373-9

Reference yield:

10.13-dimethyl-17β-((R)-4-hydroxy-1.4-dimethyl-pentyl)-5β-gonane → 23-phenyl-24-nor-5β-cholanone-(23) (55542-01-3)

Guidance literature:

Multi-step reaction with 5 steps

1: CrO₃; acetic acid

2: chromium (VI)-oxide; acetic acid

3: hydrogen chloride

4: diethyl ether / zuletzt ohne Loesungsmittel auf dem Dampfbad

5: CrO₃; aqueous acetic acid / Erhitzen des Reaktionsprodukts mit methanol. KOH und Erwaermen des danach isolierten Reaktionsprodukts mit CrO₃ in Essigsaeure

With chromium(VI) oxide; hydrogenchloride; diethyl ether; acetic acid;

Reference yield:

5β-cholanoic acid-(24)-ethyl ester (5795-90-4) → 23-phenyl-24-nor-5β-cholanone-(23) (55542-01-3)

Guidance literature:

Multi-step reaction with 6 steps

1: diethyl ether

2: CrO₃; acetic acid

3: chromium (VI)-oxide; acetic acid

4: hydrogen chloride

5: diethyl ether / zuletzt ohne Loesungsmittel auf dem Dampfbad

6: CrO₃; aqueous acetic acid / Erhitzen des Reaktionsprodukts mit methanol. KOH und Erwaermen des danach isolierten Reaktionsprodukts mit CrO₃ in Essigsaeure

With chromium(VI) oxide; hydrogenchloride; diethyl ether; acetic acid;

upstream raw materials:

10.13-dimethyl-17β-((R)-3-hydroxy-1-methyl-3.3-diphenyl-propyl)-5β-gonane

diethyl ether

24-nor-5β-cholanoic acid-(23)-ethyl ester

24-methyl-5β-cholan-24-one

Downstream raw materials:

Phenyl-23nor-5β-cholonat