Technology Process of 2-cyano-3-oxo-3-(1-phenyl-1H-benzothieno<3,2-c>pyrazol-3-yl)-N-phenyl-propanamide
There total 6 articles about 2-cyano-3-oxo-3-(1-phenyl-1H-benzothieno<3,2-c>pyrazol-3-yl)-N-phenyl-propanamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 72 percent / sodium ethoxide / ethanol / 2 h / Ambient temperature
2: 13 percent / acetic acid / 6 h at 60 deg C, 18 h reflux
3: 85 percent / 0.1N KOH / aq. ethanol / 0.33 h / Heating
4: thionyl chloride / dioxane / 1.5 h / Heating
5: 1) NaH / 1) dioxane, 2) dioxane, 1.5 h, r.t.
With
potassium hydroxide; thionyl chloride; sodium ethanolate; sodium hydride; acetic acid;
In
1,4-dioxane; ethanol;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 13 percent / acetic acid / 6 h at 60 deg C, 18 h reflux
2: 85 percent / 0.1N KOH / aq. ethanol / 0.33 h / Heating
3: thionyl chloride / dioxane / 1.5 h / Heating
4: 1) NaH / 1) dioxane, 2) dioxane, 1.5 h, r.t.
With
potassium hydroxide; thionyl chloride; sodium hydride; acetic acid;
In
1,4-dioxane; ethanol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: thionyl chloride / dioxane / 1.5 h / Heating
2: 1) NaH / 1) dioxane, 2) dioxane, 1.5 h, r.t.
With
thionyl chloride; sodium hydride;
In
1,4-dioxane;