2,6-dichloro-8-phenyl-7H-purine

Base Information

Chemical Name:2,6-dichloro-8-phenyl-7H-purine
CAS No.:412918-55-9
Molecular Formula:C₁₁H₆Cl₂N₄
Molecular Weight:265.101
Hs Code.:
DSSTox Substance ID:DTXSID90595490
Wikidata:Q82490500

Synonyms:2,6-dichloro-8-phenyl-7H-purine;412918-55-9;SCHEMBL7228428;SCHEMBL24500765;DTXSID90595490

Suppliers and Price of 2,6-dichloro-8-phenyl-7H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,6-dichloro-8-phenyl-7H-purine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:263.9969516
Heavy Atom Count:17
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=C(N2)C(=NC(=N3)Cl)Cl

Technology Process of 2,6-dichloro-8-phenyl-7H-purine

There total 2 articles about 2,6-dichloro-8-phenyl-7H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 2879-14-3
8-phenyl-9H-purine-2,6-diol

: 412918-55-9
2,6-dichloro-8-phenyl-9H-purine

Guidance literature:: With N,N-diethylaniline; trichlorophosphate; Heating;
DOI:10.1002/1521-4184(200112)334:11<345::AID-ARDP345>3.0.CO;2-1

Reference yield:

: 98-88-4
benzoyl chloride

: 412918-55-9
2,6-dichloro-8-phenyl-9H-purine

Guidance literature:: Multi-step reaction with 2 steps

1.1: Heating

1.2: 56.1 percent / aq. NaOH / Heating

2.1: 35 percent / phosphoryl chloride; diethylaniline / Heating

With N,N-diethylaniline; trichlorophosphate;
DOI:10.1002/1521-4184(200112)334:11<345::AID-ARDP345>3.0.CO;2-1

Reference yield:

: 412918-55-9
2,6-dichloro-8-phenyl-9H-purine

: (2-chloro-9-isopropyl-8-phenyl-9H-purin-6-yl)-(3-chloro-phenyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: butan-1-ol / 20 h / 90 °C

2.1: NaH / dimethylformamide / 1 h / 20 °C

2.2: dimethylformamide / 24 h

With sodium hydride; In N,N-dimethyl-formamide; butan-1-ol;
DOI:10.1002/1521-4184(200112)334:11<345::AID-ARDP345>3.0.CO;2-1