AMG-131 besylate

Base Information

• Chemical Name: AMG-131 besylate
• CAS No.: 849738-78-9
• Molecular Formula: C₆H₆O₃S*C₂₁H₁₂Cl₄N₂O₃S
• Molecular Weight: 672.394
• UNII: O591H1M24D
• Wikidata: Q27285358
• Mol file: 849738-78-9.mol

Synonyms:AMG-131 besylate;T0903131 Besylate;INT 131 besylate;O591H1M24D;849738-78-9;UNII-O591H1M24D;Benzenesulfonamide, 2,4-dichloro-N-(3,5-dichloro-4-(3-quinolinyloxy)phenyl)-, monobenzenesulfonate;IBRIGAMPAR BESYLATE;CHS-131 BESYLATE;INT-131 BESYLATE;T-0903131 Besylate;SCHEMBL634435;SB16868;Q27285358;2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide besylate;2,4-DICHLORO-N-(3,5-DICHLORO-4-((QUINOLIN-3- YL)OXY)PHENYL)BENZENE-1-SULFONAMIDE BESYLATE;BENZENESULFONAMIDE, 2,4-DICHLORO-N-(3,5-DICHLORO-4-(3-QUINOLINYLOXY)PHENYL)-, BENZENESULFONATE (1:1)

Chemical Property of AMG-131 besylate

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 671.933089
• Heavy Atom Count: 41
• Complexity: 881

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)O.C1=CC=C2C(=C1)C=C(C=N2)OC3=C(C=C(C=C3Cl)NS(=O)(=O)C4=C(C=C(C=C4)Cl)Cl)Cl
• Recent ClinicalTrials: A Safety and Efficacy Study of T0903131 (INT131) Besylate to Treat Type 2 Diabetes Mellitus

Technology Process of AMG-131 besylate

There total 1 articles about AMG-131 besylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (315224-26-1) + benzenesulfonic acid (98-11-3) → 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)-phenyl]-benzenesulfonamide benzenesulfonate salt (849738-78-9)

Guidance literature:

In ethanol;

upstream raw materials:

2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide

benzenesulfonic acid