(+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal

Base Information

• Chemical Name: (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal
• CAS No.: 77783-97-2
• Molecular Formula: C₃₀H₄₆O₆
• Molecular Weight: 502.692
• Mol file: 77783-97-2.mol

Synonyms:

Chemical Property of (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal

There total 2 articles about (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-Allyl-4-(3,4-dimethoxy-phenyl)-2-[2-(5,5-dimethyl-[1,3]dioxan-2-yl)-ethyl]-cyclohexanone (77783-95-0,77783-96-1) + 2,2-Dimethyl-1,3-propanediol (126-30-7) → (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal (77783-97-2,77783-98-3)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 18h; Heating;

DOI:10.1039/P19810000029

Reference yield:

(+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohex-2-en-1-one (77783-94-9) → (+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal (77783-97-2,77783-98-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / liquid ammonia, lithium / tetrahydrofuran / 3 h

2: 82 percent / toluene-p-sulphonic acid / toluene / 18 h / Heating

With ammonia; lithium; toluene-4-sulfonic acid; In tetrahydrofuran; toluene;

DOI:10.1039/P19810000029

Reference yield: 84.0%

(+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohexan-1-one 2,2-dimethyltrimethylene acetal (77783-97-2,77783-98-3) → (+/-)-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>-4-formylmethylcyclohexan-1-one 2,2-dimethyltrimethylene acetal (77783-99-4,77784-00-0)

Guidance literature:

With sodium periodate; osmium(VIII) oxide; In diethyl ether; water; for 18h;

DOI:10.1039/P19810000029

upstream raw materials:

4-Allyl-4-(3,4-dimethoxy-phenyl)-2-[2-(5,5-dimethyl-[1,3]dioxan-2-yl)-ethyl]-cyclohexanone

2,2-Dimethyl-1,3-propanediol

(+/-)-4-allyl-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>cyclohex-2-en-1-one

Downstream raw materials:

(+/-)-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>-4-formylmethylcyclohexan-1-one 2,2-dimethyltrimethylene acetal

(+/-)-4-(3,4-dimethoxyphenyl)-2-<2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl>-4-(2-methylaminoethyl)cyclohexan-1-one 2,2-dimethyltrimethyllene acetal

(+/-)-sceletium alkaloid A₄