trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene

Base Information

• Chemical Name: trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene
• CAS No.: 142634-72-8
• Molecular Formula: C₃₂H₃₇N₃O₅
• Molecular Weight: 543.663
• Mol file: 142634-72-8.mol

Synonyms:

Chemical Property of trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene

There total 4 articles about trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-Undecen-1-ol (112-43-6) → trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene (142634-71-7,142634-72-8,142697-92-5,149880-05-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 142 g / triethylamine / CH₂Cl₂ / 0 °C

2: 90 percent / sodium iodide, dicyclohexano-18-crown-6 / H₂O / 5 h / Heating

3: 63 percent / potassium tert-butoxide / benzene / a) 40 deg C, 45 min, 2) reflux, 2 h

4: 5.9 g / sodium cyanoborohydride, ammonium acetate / propan-2-ol / 24 h / 90 - 95 °C

5: aq. sodium hydrogen carbonate / CH₂Cl₂ / 1 h

With ammonium acetate; perhydrodibenzo-18-crown-6; potassium tert-butylate; sodium cyanoborohydride; sodium hydrogencarbonate; triethylamine; sodium iodide; In dichloromethane; water; isopropyl alcohol; benzene;

DOI:10.1021/jo00040a026

Reference yield:

undec-10-en-1-yl methanesulfonate (52355-50-7) → trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene (142634-71-7,142634-72-8,142697-92-5,149880-05-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / sodium iodide, dicyclohexano-18-crown-6 / H₂O / 5 h / Heating

2: 63 percent / potassium tert-butoxide / benzene / a) 40 deg C, 45 min, 2) reflux, 2 h

3: 5.9 g / sodium cyanoborohydride, ammonium acetate / propan-2-ol / 24 h / 90 - 95 °C

4: aq. sodium hydrogen carbonate / CH₂Cl₂ / 1 h

With ammonium acetate; perhydrodibenzo-18-crown-6; potassium tert-butylate; sodium cyanoborohydride; sodium hydrogencarbonate; sodium iodide; In dichloromethane; water; isopropyl alcohol; benzene;

DOI:10.1021/jo00040a026

Reference yield:

4-oxo-3-undec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene (142634-68-2) → trans-4-(3,5-dinitrobenzamido)-3-indec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene (142634-71-7,142634-72-8,142697-92-5,149880-05-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 5.9 g / sodium cyanoborohydride, ammonium acetate / propan-2-ol / 24 h / 90 - 95 °C

2: aq. sodium hydrogen carbonate / CH₂Cl₂ / 1 h

With ammonium acetate; sodium cyanoborohydride; sodium hydrogencarbonate; In dichloromethane; isopropyl alcohol;

DOI:10.1021/jo00040a026

upstream raw materials:

4-amino-3-undec-10-en-1-yl-1,2,3,4-tetrahydrophenanthrene

3,5-dinitrobenoyl chloride

10-Undecen-1-ol

undec-10-en-1-yl methanesulfonate