C₂₃H₁₉F₃N₄O₄

Base Information

• Chemical Name: C₂₃H₁₉F₃N₄O₄
• CAS No.: 945224-76-0
• Molecular Formula: C₂₃H₁₉F₃N₄O₄
• Molecular Weight: 472.423
• Mol file: 945224-76-0.mol

Synonyms:

Chemical Property of C₂₃H₁₉F₃N₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₁₉F₃N₄O₄

There total 3 articles about C₂₃H₁₉F₃N₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-iodo-5-(trifluoromethyl)biphenyl-2,4-dicarbonitrile (853052-83-2) → C23H19F3N4O4 (945224-76-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 2 h / Heating

2: acetic acid / 0.02 h / microwave irradiation

With hydrazine hydrate; acetic acid; In ethanol;

DOI:10.1016/j.bmcl.2007.03.087

Reference yield:

3-trifluoromethyl-5-phenyl-2,6-dicyanoaniline (86439-16-9) → C23H19F3N4O4 (945224-76-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: aq. HCl; NaNO₂ / acetonitrile / 0 °C

1.2: potassium iodide / H₂O; acetonitrile

2.1: hydrazine hydrate / ethanol / 2 h / Heating

3.1: acetic acid / 0.02 h / microwave irradiation

With hydrogenchloride; hydrazine hydrate; acetic acid; sodium nitrite; In ethanol; acetonitrile;

DOI:10.1016/j.bmcl.2007.03.087

Reference yield:

C15H9F3N4 (945224-60-2) + diethyl N,N-dimethylaminomethylenemalonate (18856-68-3) → C23H19F3N4O4 (945224-76-0)

Guidance literature:

With acetic acid; for 0.0166667h; microwave irradiation;

DOI:10.1016/j.bmcl.2007.03.087

upstream raw materials:

C₁₅H₉F₃N₄

diethyl N,N-dimethylaminomethylenemalonate

3-iodo-5-(trifluoromethyl)biphenyl-2,4-dicarbonitrile

3-trifluoromethyl-5-phenyl-2,6-dicyanoaniline